Role of Systematic Lymphadenectomy and Adjuvant Radiation in Early-Stage Endometrioid Uterine Cancer
DC Field | Value | Language |
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dc.contributor.author | Jeong, Nan-Hee | - |
dc.contributor.author | Lee, Jong-Min | - |
dc.contributor.author | Lee, Jae-Kwan | - |
dc.contributor.author | Kim, Mi-Kyung | - |
dc.contributor.author | Kim, Young-Jae | - |
dc.contributor.author | Cho, Chi-Heum | - |
dc.contributor.author | Kim, Seok-Mo | - |
dc.contributor.author | Park, Sang-Yoon | - |
dc.contributor.author | Park, Chan-Yong | - |
dc.contributor.author | Kim, Ki-Tae | - |
dc.date.accessioned | 2021-09-07T23:21:04Z | - |
dc.date.available | 2021-09-07T23:21:04Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2010-11 | - |
dc.identifier.issn | 1068-9265 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/115460 | - |
dc.description.abstract | Objective. To determine the roles of lymphadenectomy in endometrioid uterine cancer patients and adjuvant radiation in early-stage endometrioid uterine cancer patients who underwent systematic lymphadenectomy. Methods. A retrospective analysis of 758 patients surgically treated for early-stage endometrioid uterine cancer from 2000 to 2006 was conducted. The primary outcome was 5-year overall survival in relation to systematic lymphadenectomy with or without adjuvant radiation. Results. Of the 758 patients, 547 (72.2%) underwent complete surgical staging, including systematic lymphadenectomy; adjuvant radiation was administered to 207 patients (27.3%). Within median follow-up of 35 months, systematic lymphadenectomy did not affect overall survival in early-stage patients (P = 0.4480). In the high-risk, early-stage group, however, the 5-year survival rate of the systematic lymphadenectomy group showed better survival compared with the no systematic lymphadenectomy group (P = 0.0095). Also, adjuvant radiation did not affect overall survival in early-stage patients (P = 0.1170), even in the group of high-risk, early-stage patients (P = 0.5680) who underwent systematic lymphadenectomy. Conclusions. Systematic lymphadenectomy provided a survival benefit in high-risk endometrioid uterine cancer patients. However, in patients who underwent systematic lymphadenectomy, adjuvant radiation was not beneficial, even in high-risk patients. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.subject | PHASE-III TRIAL | - |
dc.subject | POSTOPERATIVE RADIOTHERAPY | - |
dc.subject | PELVIC LYMPHADENECTOMY | - |
dc.subject | MRC ASTEC | - |
dc.subject | CARCINOMA | - |
dc.subject | IRRADIATION | - |
dc.subject | SURVIVAL | - |
dc.subject | OUTCOMES | - |
dc.subject | SURGERY | - |
dc.title | Role of Systematic Lymphadenectomy and Adjuvant Radiation in Early-Stage Endometrioid Uterine Cancer | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Jae-Kwan | - |
dc.identifier.doi | 10.1245/s10434-010-1169-y | - |
dc.identifier.scopusid | 2-s2.0-78049476170 | - |
dc.identifier.wosid | 000283400900021 | - |
dc.identifier.bibliographicCitation | ANNALS OF SURGICAL ONCOLOGY, v.17, no.11, pp.2951 - 2957 | - |
dc.relation.isPartOf | ANNALS OF SURGICAL ONCOLOGY | - |
dc.citation.title | ANNALS OF SURGICAL ONCOLOGY | - |
dc.citation.volume | 17 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 2951 | - |
dc.citation.endPage | 2957 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | PHASE-III TRIAL | - |
dc.subject.keywordPlus | POSTOPERATIVE RADIOTHERAPY | - |
dc.subject.keywordPlus | PELVIC LYMPHADENECTOMY | - |
dc.subject.keywordPlus | MRC ASTEC | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | IRRADIATION | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | SURGERY | - |
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