Incidence and natural history of coronary artery aneurysm developing after drug-eluting stent implantation
- Authors
- Ahn, Chul-Min; Hong, Bum-Kee; Kim, Jong-Youn; Min, Pil-Ki; Yoon, Young W.; Lee, Byoung K.; Kwon, Hyuck M.; Kim, Jung-Sun; Ko, Young-Guk; Choi, Donghoon; Hong, Myeong-Ki; Jang, Yangsoo; Shim, Won-Heum; Cho, Seung-Yun; Kim, Byeong-Keuk; Oh, Seongjin; Jeon, Dong W.; Yang, Joo Y.; Jung, Jae-Hun
- Issue Date
- 11월-2010
- Publisher
- MOSBY-ELSEVIER
- Citation
- AMERICAN HEART JOURNAL, v.160, no.5, pp.987 - 994
- Indexed
- SCIE
SCOPUS
- Journal Title
- AMERICAN HEART JOURNAL
- Volume
- 160
- Number
- 5
- Start Page
- 987
- End Page
- 994
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/115477
- DOI
- 10.1016/j.ahj.2010.07.013
- ISSN
- 0002-8703
- Abstract
- Aims There is a growing concern about the occurrence of coronary artery aneurysms (CAAs) after drug-eluting stent (DES) implantation and their long-term course. We assessed the occurrence and the factors affecting the long-term outcome of DES-associated CAA. Methods and Results We analyzed 3,612 consecutive patients (4,419 lesions) who underwent follow-up angiography after DES implantation. All 34 CAAs (0.76% per lesion) in 29 patients (0.8% per patient) were detected at follow-up, and the mean elapsed time from DES implantation to CAA diagnosis was 414 +/- 213 days. Angiographically, CAAs developed almost exclusively in complex (type B2/C) de novo lesions (30 [88.2%] of 34 lesions), and lesion length was significantly greater in patients with CAA than without CAA (26.9 +/- 9.03 vs 23.1 +/- 7.14 mm; P = .004). Myocardial infarction with stent thrombosis occurred in 5 patients with CAA (17.2%), 4 of whom were on aspirin only without clopidogrel. Conclusion Although CAAs rarely develop after DES implantation and show mostly favorable clinical courses, long-term maintenance of clopidogrel therapy might be required to minimize occurrence of adverse clinical events resulting from stent thrombosis. (Am Heart J 2010; 160: 987-94.)
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