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Core/Shell Nanoparticles for pH-Sensitive Delivery of Doxorubicin
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Oh, Keun Sang | - |
| dc.contributor.author | Um, Yun Sik | - |
| dc.contributor.author | Lee, Jin Ho | - |
| dc.contributor.author | Cho, Sun Hang | - |
| dc.contributor.author | Lee, Kyung Eun | - |
| dc.contributor.author | Han, Sung Sik | - |
| dc.contributor.author | Kim, Dongmin | - |
| dc.contributor.author | Yuk, Soon Hong | - |
| dc.date.accessioned | 2021-09-07T23:55:03Z | - |
| dc.date.available | 2021-09-07T23:55:03Z | - |
| dc.date.created | 2021-06-14 | - |
| dc.date.issued | 2010-10 | - |
| dc.identifier.issn | 1533-4880 | - |
| dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/115602 | - |
| dc.description.abstract | Core/shell nanoparticles with lipid core were prepared and characterized as pH-sensitive delivery system of anticancer drug. The lipid core is composed of drug-loaded lecithin and the polymeric shell is composed of Pluronics (poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer, F-127). Based on the preparation method in the previous report by us, the freeze-drying of drug-loaded lecithin was performed in the F-127 aqueous solution containing trehalose used as a cryoprotectant to form stabilized core/shell nanoparticles. For the application of core/shell nanoparticles as a pH-sensitive drug delivery system for anticancer drug, doxorubicin was loaded into the core/shell nanoparticles and the drug loading amount and drug release behavior in response to pH change were observed. | - |
| dc.language | English | - |
| dc.language.iso | en | - |
| dc.publisher | AMER SCIENTIFIC PUBLISHERS | - |
| dc.subject | MICELLES | - |
| dc.subject | PROTEINS | - |
| dc.subject | POLYMERS | - |
| dc.title | Core/Shell Nanoparticles for pH-Sensitive Delivery of Doxorubicin | - |
| dc.type | Article | - |
| dc.contributor.affiliatedAuthor | Han, Sung Sik | - |
| dc.contributor.affiliatedAuthor | Yuk, Soon Hong | - |
| dc.identifier.doi | 10.1166/jnn.2010.2986 | - |
| dc.identifier.wosid | 000280361400116 | - |
| dc.identifier.bibliographicCitation | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, v.10, no.10, pp.6967 - 6971 | - |
| dc.relation.isPartOf | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | - |
| dc.citation.title | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | - |
| dc.citation.volume | 10 | - |
| dc.citation.number | 10 | - |
| dc.citation.startPage | 6967 | - |
| dc.citation.endPage | 6971 | - |
| dc.type.rims | ART | - |
| dc.type.docType | Article; Proceedings Paper | - |
| dc.description.journalClass | 1 | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
| dc.relation.journalResearchArea | Materials Science | - |
| dc.relation.journalResearchArea | Physics | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
| dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
| dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
| dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
| dc.relation.journalWebOfScienceCategory | Physics, Condensed Matter | - |
| dc.subject.keywordPlus | MICELLES | - |
| dc.subject.keywordPlus | PROTEINS | - |
| dc.subject.keywordPlus | POLYMERS | - |
| dc.subject.keywordAuthor | Core/Shell Nanoparticles with Drug-Loaded Lipid Cores | - |
| dc.subject.keywordAuthor | Lecithin | - |
| dc.subject.keywordAuthor | Pluronics | - |
| dc.subject.keywordAuthor | pH-Sensitive Release of Anticancer Drug | - |
| dc.subject.keywordAuthor | Doxorubicin | - |
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Related Researcher
- Yuk, Soon Hong
- College of Pharmacy (Department of Pharmaceutical Science)