Rationally Designed Fluorescence Turn-On Sensors: A New Design Strategy Based on Orbital Control
DC Field | Value | Language |
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dc.contributor.author | Jung, Hyo Sung | - |
dc.contributor.author | Ko, Kyoung Chul | - |
dc.contributor.author | Lee, Jae Hong | - |
dc.contributor.author | Kim, Sang Hoon | - |
dc.contributor.author | Bhuniya, Sankarprasad | - |
dc.contributor.author | Lee, Jin Yong | - |
dc.contributor.author | Kim, Youngmee | - |
dc.contributor.author | Kim, Sung Jin | - |
dc.contributor.author | Kim, Jong Seung | - |
dc.date.accessioned | 2021-09-08T00:12:45Z | - |
dc.date.available | 2021-09-08T00:12:45Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2010-09-20 | - |
dc.identifier.issn | 0020-1669 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/115669 | - |
dc.description.abstract | Herein, we explore a new strategy in the chemo-sensor field for fluorescence amplification upon binding with metal ions based on controlled participation of the nitrogen lone pair orbital. The basic architecture of the sensor entails a fluorophore, the sp(2) hybridized nitrogen lone pair (-C=N-), and a chelator site referred to as the control part. Though nonplanar and nonfluorescent, compound IC1 achieved pseudo planarity from binding with Zn2+ as indicated by the increased fluorescence signal. Its other analogue (IC2) is also planar, and unlike IC1-Zn2+ was fluorescent with a lack of binding affinity to metal ions. The time-dependent density functional theory (TDDFT) calculations revealed that the fluorescence amplification was due to the blocking of the nitrogen lone pair orbital; unlikely geometrical rearrangements were insignificant. This could indicate a breakthrough concept in the future design of fluorescent turn-on sensors. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.subject | LIVING CELLS | - |
dc.subject | SIGNALING MECHANISM | - |
dc.subject | AQUEOUS-SOLUTION | - |
dc.subject | METAL-IONS | - |
dc.subject | ZINC IONS | - |
dc.subject | LOWER-RIM | - |
dc.subject | CHEMOSENSOR | - |
dc.subject | RECOGNITION | - |
dc.subject | EXCIMER | - |
dc.subject | CATION | - |
dc.title | Rationally Designed Fluorescence Turn-On Sensors: A New Design Strategy Based on Orbital Control | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Jong Seung | - |
dc.identifier.doi | 10.1021/ic101165k | - |
dc.identifier.scopusid | 2-s2.0-77956537423 | - |
dc.identifier.wosid | 000281630000045 | - |
dc.identifier.bibliographicCitation | INORGANIC CHEMISTRY, v.49, no.18, pp.8552 - 8557 | - |
dc.relation.isPartOf | INORGANIC CHEMISTRY | - |
dc.citation.title | INORGANIC CHEMISTRY | - |
dc.citation.volume | 49 | - |
dc.citation.number | 18 | - |
dc.citation.startPage | 8552 | - |
dc.citation.endPage | 8557 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Inorganic & Nuclear | - |
dc.subject.keywordPlus | LIVING CELLS | - |
dc.subject.keywordPlus | SIGNALING MECHANISM | - |
dc.subject.keywordPlus | AQUEOUS-SOLUTION | - |
dc.subject.keywordPlus | METAL-IONS | - |
dc.subject.keywordPlus | ZINC IONS | - |
dc.subject.keywordPlus | LOWER-RIM | - |
dc.subject.keywordPlus | CHEMOSENSOR | - |
dc.subject.keywordPlus | RECOGNITION | - |
dc.subject.keywordPlus | EXCIMER | - |
dc.subject.keywordPlus | CATION | - |
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