Control of the Haemodynamic Response to Surgical Stimuli in Semi-closed Circuit or Closed Circuit Anaesthesia Using a Multifunctional Anaesthesia System
- Authors
- Choi, S. U.; Shin, H. W.; Jung, H. I.; Park, J. Y.; Yoon, S. Z.; Lee, Y. S.; Kim, W. Y.; Chang, S. H.
- Issue Date
- 9월-2010
- Publisher
- FIELD HOUSE PUBLISHING LLP
- Keywords
- ANAESTHESIA; CLOSED CIRCUIT; SEMI-CLOSED CIRCUIT; HAEMODYNAMIC CONTROL; SEVOFLURANE
- Citation
- JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, v.38, no.5, pp.1637 - 1644
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- Volume
- 38
- Number
- 5
- Start Page
- 1637
- End Page
- 1644
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/115784
- DOI
- 10.1177/147323001003800508
- ISSN
- 0300-0605
- Abstract
- This study compared the ability of the Zeus (R) multifunctional anaesthesia system to control haemodynamic response to surgical stimulation in semi-closed (SCA) or closed circuit anaesthesia (CCA) modes. Fifty patients undergoing gynaecological surgery were randomly assigned to SCA or CCA. Anaesthesia was induced with 2 mg propofol and 0.9 mg/kg rocuronium, intravenously, and maintained using sevoflurane (minimum alveolar concentration [MAC], 1.0) using 2 l/min oxygen plus 2 l/min nitrous oxide (SCA 4 l/min group) or 50% oxygen plus 50% nitrous oxide (CCA group). An increase in mean arterial pressure (MAP) > 20% above baseline in response to surgical stimulation provoked a stepwise increase in sevoflurane (1.3 MAC and then 1.6 MAC), followed by fentanyl 1 mu g/kg intravenously (rescue drug). The time required for MAP to return to within 10% of baseline was significantly shorter in the CCA group (6.4 +/- 3.6 min) compared with the SCA 4 l/min group (10.2 +/- 6.0 min). The percentage of patients requiring fentanyl was significantly greater in the SCA 4 l/min group than in the CCA group. In conclusion, CCA controlled acute haemodynamic responses to surgical stimuli more successfully and rapidly than SCA 4 l/min, using a multifunctional anaesthesia machine.
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