Factors that affect the diagnostic accuracy of liver fibrosis measurement by Fibroscan in patients with chronic hepatitis B
DC Field | Value | Language |
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dc.contributor.author | Kim, S. U. | - |
dc.contributor.author | Seo, Y. S. | - |
dc.contributor.author | Cheong, J. Y. | - |
dc.contributor.author | Kim, M. Y. | - |
dc.contributor.author | Kim, J. K. | - |
dc.contributor.author | Um, S. H. | - |
dc.contributor.author | Cho, S. W. | - |
dc.contributor.author | Paik, S. K. | - |
dc.contributor.author | Lee, K. S. | - |
dc.contributor.author | Han, K. -H. | - |
dc.contributor.author | Ahn, S. H. | - |
dc.date.accessioned | 2021-09-08T01:02:57Z | - |
dc.date.available | 2021-09-08T01:02:57Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2010-08-01 | - |
dc.identifier.issn | 0269-2813 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/115903 | - |
dc.description.abstract | P>Background Interquartile range/median value (IQR/M) of liver stiffness measurement (LSM) is a factor in chronic hepatitis C (CHC) leading to over estimation of fibrosis by Fibroscan. Aim To investigate factors that affect the accuracy of LSM in chronic hepatitis B (CHB). Methods One hundred and ninety-nine patients were enrolled. Only procedures yielding >= 10 valid measurements were considered reliable. Liver fibrosis was evaluated using the Batts and Ludwig system. Liver biopsy (LB) specimens < 15 mm were considered ineligible. Results The mean age (142 men and 57 women) was 40.1 years. A significant discordance (discordance of at least two stages between LB and LSM) was identified in 38 (19.1%) and 47 (23.6%) patients respectively, according to Marcellin et al. and Chan et al.'s cutoff values. In multivariate analyses, BMI and fibrosis stage (F0-2 vs. F3-4) were identified as independent predictors for significant discordance (P = 0.040; hazard ratio [HR], 1.126; 95% confidence interval [CI], 1.005-1.261 and P = 0.036; HR, 0.450; 95% CI, 0.213-0.949 respectively) with Marcellin et al.'s cutoffs, whereas fibrosis stage was the only independent predictor (P = 0.004; HR, 0.300; 95% CI, 0.131-0.685) with Chan's cutoffs. Conclusions Success rate and IQR/M were not predictive factors of the accuracy for diagnosing liver fibrosis by Fibroscan in CHB. Fibrosis stage (F0-2) was the only factor to predict significant discordance between LB and LSM. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.subject | TRANSIENT ELASTOGRAPHY FIBROSCAN | - |
dc.subject | STIFFNESS MEASUREMENT | - |
dc.subject | MARKER | - |
dc.subject | VARIABILITY | - |
dc.subject | PERFORMANCE | - |
dc.subject | VALUES | - |
dc.title | Factors that affect the diagnostic accuracy of liver fibrosis measurement by Fibroscan in patients with chronic hepatitis B | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Seo, Y. S. | - |
dc.contributor.affiliatedAuthor | Um, S. H. | - |
dc.identifier.doi | 10.1111/j.1365-2036.2010.04353.x | - |
dc.identifier.scopusid | 2-s2.0-77954333877 | - |
dc.identifier.wosid | 000279611800020 | - |
dc.identifier.bibliographicCitation | ALIMENTARY PHARMACOLOGY & THERAPEUTICS, v.32, no.3, pp.498 - 505 | - |
dc.relation.isPartOf | ALIMENTARY PHARMACOLOGY & THERAPEUTICS | - |
dc.citation.title | ALIMENTARY PHARMACOLOGY & THERAPEUTICS | - |
dc.citation.volume | 32 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 498 | - |
dc.citation.endPage | 505 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | TRANSIENT ELASTOGRAPHY FIBROSCAN | - |
dc.subject.keywordPlus | STIFFNESS MEASUREMENT | - |
dc.subject.keywordPlus | MARKER | - |
dc.subject.keywordPlus | VARIABILITY | - |
dc.subject.keywordPlus | PERFORMANCE | - |
dc.subject.keywordPlus | VALUES | - |
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