Novel Streptavidin-Functionalized Silicon Nanowire Arrays for CD4(+) T Lymphocyte Separation
DC Field | Value | Language |
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dc.contributor.author | Kim, Sung Tae | - |
dc.contributor.author | Kim, Dong-Joo | - |
dc.contributor.author | Kim, Tae-Jin | - |
dc.contributor.author | Seo, Deok-Won | - |
dc.contributor.author | Kim, Tae-Hong | - |
dc.contributor.author | Lee, Seung-Yong | - |
dc.contributor.author | Kim, Kwanghee | - |
dc.contributor.author | Lee, Kyung-Mi | - |
dc.contributor.author | Lee, Sang-Kwon | - |
dc.date.accessioned | 2021-09-08T01:12:45Z | - |
dc.date.available | 2021-09-08T01:12:45Z | - |
dc.date.created | 2021-06-14 | - |
dc.date.issued | 2010-08 | - |
dc.identifier.issn | 1530-6984 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/115959 | - |
dc.description.abstract | Silicon nanowires (SiNWs) offer promising inorganic nanostructures for biomedical application. Here, we report the development of a novel SiNW array designed for isolating primary CD4(+) T lymphocytes from the heterogeneous mixture of cell populations. Our system employed the specific high-affinity binding features of streptavidin (STR)-functionalizeci SiNW with biotin-labeled CD4(+) T lymphocytes. Fabricated SiNW arrays easily separated the CD4(+) T lymphocytes from the mouse whole splenocytes with over similar to 88% purity and demonstrated tight attachment to CD4(+) T lymphocytes by scanning electron microscopy. Thus, our STR-SiNW arrays provide a potential tool for specific cell separation and further present a possibility to be applied to the other area of biomedical applications. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.subject | MAGNETIC CELL-SEPARATION | - |
dc.subject | NATURAL-KILLER-CELLS | - |
dc.subject | SENSORS | - |
dc.subject | DNA | - |
dc.title | Novel Streptavidin-Functionalized Silicon Nanowire Arrays for CD4(+) T Lymphocyte Separation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Sung Tae | - |
dc.contributor.affiliatedAuthor | Lee, Kyung-Mi | - |
dc.identifier.doi | 10.1021/nl100942p | - |
dc.identifier.scopusid | 2-s2.0-77955565572 | - |
dc.identifier.wosid | 000280728900024 | - |
dc.identifier.bibliographicCitation | NANO LETTERS, v.10, no.8, pp.2877 - 2883 | - |
dc.relation.isPartOf | NANO LETTERS | - |
dc.citation.title | NANO LETTERS | - |
dc.citation.volume | 10 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 2877 | - |
dc.citation.endPage | 2883 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.relation.journalWebOfScienceCategory | Physics, Condensed Matter | - |
dc.subject.keywordPlus | MAGNETIC CELL-SEPARATION | - |
dc.subject.keywordPlus | NATURAL-KILLER-CELLS | - |
dc.subject.keywordPlus | SENSORS | - |
dc.subject.keywordPlus | DNA | - |
dc.subject.keywordAuthor | Silicon nanowire | - |
dc.subject.keywordAuthor | streptavidin | - |
dc.subject.keywordAuthor | CD4(+) T lymphocyte | - |
dc.subject.keywordAuthor | cell separation | - |
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