Cut-Off Value for Needle Washout Thyroglobulin in Athyrotropic Patients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Young Hen | - |
dc.contributor.author | Seo, Hyung Suk | - |
dc.contributor.author | Suh, Sang-il | - |
dc.contributor.author | Lee, Nam Joon | - |
dc.contributor.author | Kim, Jung Hyuk | - |
dc.contributor.author | Seol, Hae Young | - |
dc.contributor.author | Lee, Ju-Han | - |
dc.contributor.author | Kwon, Soon-Young | - |
dc.contributor.author | Kim, Nan Hee | - |
dc.contributor.author | Seo, Ji A. | - |
dc.contributor.author | Yang, Kyung-Sook | - |
dc.date.accessioned | 2021-09-08T02:53:46Z | - |
dc.date.available | 2021-09-08T02:53:46Z | - |
dc.date.created | 2021-06-11 | - |
dc.date.issued | 2010-06 | - |
dc.identifier.issn | 0023-852X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/116386 | - |
dc.description.abstract | Objectives/Hypothesis: The purpose of this study was to determine the appropriate cut-off value for fine needle aspiration-thyroglobulin (FNA-Tg) associated with postoperative recurrences and validate the diagnostic efficacy of FNA-Tg in patients after total thyroidectomy compared with concomitant cytology (C). Study Design: Retrospective. Methods: We retrospectively evaluated the results of ultrasound-guided FNAs performed for suspicious cervical lesions of 40 patients (male:female = 10:30; mean age, 44.0 years) after total thyroidectomy (mean duration, 89.1 months), to acquire the material for Tg and C analysis. After collection of the cytologic sample, we rinsed the same needle with 1 mL of normal saline for Tg radioimmunoassay. Results: Of 40 lesions (mean size, 0.89 cm; range, 0.3-3.5cm), 21 were confirmed as recurrences and 19 were nonrecurrences. The rates of nondiagnostic sampling and sensitivity and specificity of FNA-C when diagnostic sampling was obtained were 40% (16/40), 100% (14/14), and 90.0% (9/10), respectively. According to receiver operating characteristic analysis, the optimal cut-off value of FNA-Tg was 4.1 ng/mL (sensitivity, 100% [21/21]; specificity, 100% [19/19], P < .05). Furthermore, in 16 in conclusive lesions due to nondiagnostic cytologic results, the FNA-Tg results coincided with a final diagnosis (seven recurrences and nine nonrecurrences). The cases with maximum diameters <1 cm showed a significantly increased rate of nondiagnostic cytologic results, and the FNA-Tg results were more helpful than lesions >= 1 cm in diagnosing a recurrence (P < .05). Conclusions: Measurement of FNA-Tg is helpful for distinguishing recurrent from nonrecurrent lesions in the majority of patients who were previously treated for well-differentiated papillary thyroid carcinoma. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | JOHN WILEY & SONS INC | - |
dc.subject | DIFFERENTIATED THYROID-CARCINOMA | - |
dc.subject | CERVICAL LYMPH-NODES | - |
dc.subject | ASPIRATION BIOPSY | - |
dc.subject | CANCER | - |
dc.subject | PAPILLARY | - |
dc.subject | DIAGNOSIS | - |
dc.subject | METASTASES | - |
dc.subject | SONOGRAPHY | - |
dc.title | Cut-Off Value for Needle Washout Thyroglobulin in Athyrotropic Patients | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Young Hen | - |
dc.contributor.affiliatedAuthor | Seo, Hyung Suk | - |
dc.contributor.affiliatedAuthor | Suh, Sang-il | - |
dc.contributor.affiliatedAuthor | Lee, Nam Joon | - |
dc.contributor.affiliatedAuthor | Kim, Jung Hyuk | - |
dc.contributor.affiliatedAuthor | Seol, Hae Young | - |
dc.contributor.affiliatedAuthor | Lee, Ju-Han | - |
dc.contributor.affiliatedAuthor | Kwon, Soon-Young | - |
dc.contributor.affiliatedAuthor | Kim, Nan Hee | - |
dc.contributor.affiliatedAuthor | Seo, Ji A. | - |
dc.identifier.doi | 10.1002/lary.20893 | - |
dc.identifier.scopusid | 2-s2.0-77953174789 | - |
dc.identifier.wosid | 000278479600008 | - |
dc.identifier.bibliographicCitation | LARYNGOSCOPE, v.120, no.6, pp.1120 - 1124 | - |
dc.relation.isPartOf | LARYNGOSCOPE | - |
dc.citation.title | LARYNGOSCOPE | - |
dc.citation.volume | 120 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1120 | - |
dc.citation.endPage | 1124 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Research & Experimental Medicine | - |
dc.relation.journalResearchArea | Otorhinolaryngology | - |
dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
dc.relation.journalWebOfScienceCategory | Otorhinolaryngology | - |
dc.subject.keywordPlus | DIFFERENTIATED THYROID-CARCINOMA | - |
dc.subject.keywordPlus | CERVICAL LYMPH-NODES | - |
dc.subject.keywordPlus | ASPIRATION BIOPSY | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | PAPILLARY | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | METASTASES | - |
dc.subject.keywordPlus | SONOGRAPHY | - |
dc.subject.keywordAuthor | Cervical recurrence | - |
dc.subject.keywordAuthor | sonography | - |
dc.subject.keywordAuthor | thyroid cancer | - |
dc.subject.keywordAuthor | thyroglobulin | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.