Dedifferentiated liposarcoma of retroperitoneum: spectrum of imaging findings in 15 patients
- Authors
- Hong, Sun Hwa; Kim, Kyeong Ah; Woo, Ok Hee; Park, Cheol Min; Kim, Chul Hwan; Kim, Myeong-Jin; Chung, Jae-Joon; Han, Joon Koo; Rha, Sung Eun
- Issue Date
- 5월-2010
- Publisher
- ELSEVIER SCIENCE INC
- Keywords
- Liposarcoma; Dedifferentiated; Retroperitoneum; CT; MR; Pathology
- Citation
- CLINICAL IMAGING, v.34, no.3, pp.203 - 210
- Indexed
- SCIE
SCOPUS
- Journal Title
- CLINICAL IMAGING
- Volume
- 34
- Number
- 3
- Start Page
- 203
- End Page
- 210
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/116485
- DOI
- 10.1016/j.clinimag.2009.12.025
- ISSN
- 0899-7071
- Abstract
- Background: Dedifferentiated liposarcoma is a high-grade nonlipogenic sarcoma that arises in the background of a preexisting well-differentiated liposarcoma. The purpose of this work is to evaluate the spectrum of radiologic appearance of retroperitoneal dedifferentiated liposarcoma with clinicopathologic features. Methods: Radiologic images and clinical histories of 15 patients with histologically verified retroperitoneal dedifferentiated liposarcoma were retrospectively studied. Patients included 11 men and 4 women, with mean age of 55.8 years (range, 36-74 years), and they underwent computed tomography (CT) (n=15) and magnetic resonance imaging (MRI) (n=5). Results: The mean size of the tumor was 22.6 cm with a range of 9.5-38 cm. Both CT and MRI showed well-circumscribed, large round, or lobulated retroperitoneal mass. The appearance of the tumor was classified as follows: Category I, nonfatty component within predominant fatty mass (n=5); Category II, focal fatty component within large nonfatty mass (n=6); Category III, well-defined fatty mass and well-defined nonfatty mass (n=1); Category IV, two masses with predominantly nonfatty component (n=3). Conclusion: Retroperitoneal dedifferentiated liposarcomas present various spectra of imaging findings. While Categories I and III may suggest dedifferentiated liposarcoma, Categories II and IV may appear as other types of liposarcoma or other malignant retroperitoneal tumor. (C) 2010 Elsevier Inc. All rights reserved.
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