Effects of glucose level on early and long-term mortality after intracerebral haemorrhage: the Acute Brain Bleeding Analysis Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, S. -H. | - |
dc.contributor.author | Kim, B. J. | - |
dc.contributor.author | Bae, H. -J. | - |
dc.contributor.author | Lee, J. S. | - |
dc.contributor.author | Lee, J. | - |
dc.contributor.author | Park, B. -J. | - |
dc.contributor.author | Yoon, B. -W. | - |
dc.date.accessioned | 2021-09-08T04:47:25Z | - |
dc.date.available | 2021-09-08T04:47:25Z | - |
dc.date.created | 2021-06-11 | - |
dc.date.issued | 2010-03 | - |
dc.identifier.issn | 0012-186X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/116883 | - |
dc.description.abstract | Admission hyperglycaemia is associated with a poor outcome in patients with ischaemic stroke. However, its prognostic effects after intracerebral haemorrhage (ICH) are still unclear. We prospectively enrolled patients with ICH at 33 centres in Korea between October 2002 and March 2004. A total of 1,387 patients who had ICH and underwent brain computed tomography within 48 h of symptom onset were included in the study (n = 1,387). Clinical information and radiological findings were collected at admission. Glucose levels were examined in relation to early (up to 30 days after ictus) and long-term (after 30 days) mortality rates using Cox regression analysis. To eliminate short-term effects, long-term mortality rate analysis was performed on surviving patients for more than 30 days. The long-term mortality rate was 21.1% after a mean follow-up of 434.3 +/- 223.2 days and was found to increase significantly with glucose quartile (p < 0.001). Admission glucose level was an independent risk factor for early mortality (per mmol/l; adjusted HR 1.10 [95% CI 1.01-1.19]), but not for long-term mortality. Moreover, when analysis was restricted to patients without diabetes, glucose level was found to be an independent risk factor for post-ICH mortality (n = 1,119; adjusted HR 1.10 [95% CI 1.03-1.17]) and had marginal significance for early (p = 0.053) and long-term mortality (p = 0.09). We found that admission glucose levels were associated with early mortality after ICH. In patients without diabetes, admission glucose levels were associated with long-term mortality. We therefore suggest that intensive lowering of glucose level should be further investigated in ICH patients. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.subject | ACUTE STROKE | - |
dc.subject | PROGNOSTIC-FACTORS | - |
dc.subject | HYPERGLYCEMIA | - |
dc.subject | SURVIVAL | - |
dc.subject | PREDICTION | - |
dc.subject | ASSOCIATION | - |
dc.subject | INSULIN | - |
dc.subject | STRESS | - |
dc.subject | EDEMA | - |
dc.subject | MODEL | - |
dc.title | Effects of glucose level on early and long-term mortality after intracerebral haemorrhage: the Acute Brain Bleeding Analysis Study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, J. | - |
dc.identifier.doi | 10.1007/s00125-009-1617-z | - |
dc.identifier.scopusid | 2-s2.0-77949271513 | - |
dc.identifier.wosid | 000274238500005 | - |
dc.identifier.bibliographicCitation | DIABETOLOGIA, v.53, no.3, pp.429 - 434 | - |
dc.relation.isPartOf | DIABETOLOGIA | - |
dc.citation.title | DIABETOLOGIA | - |
dc.citation.volume | 53 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 429 | - |
dc.citation.endPage | 434 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.subject.keywordPlus | ACUTE STROKE | - |
dc.subject.keywordPlus | PROGNOSTIC-FACTORS | - |
dc.subject.keywordPlus | HYPERGLYCEMIA | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | PREDICTION | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | INSULIN | - |
dc.subject.keywordPlus | STRESS | - |
dc.subject.keywordPlus | EDEMA | - |
dc.subject.keywordPlus | MODEL | - |
dc.subject.keywordAuthor | Glucose | - |
dc.subject.keywordAuthor | Intracerebral haemorrhage | - |
dc.subject.keywordAuthor | Mortality | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.