Anti-adhesive Effect and Safety of Sodium Hyaluronate and Sodium Carboxymethyl Cellulose Solution in Thyroid Surgery
DC Field | Value | Language |
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dc.contributor.author | Park, Won Seo | - |
dc.contributor.author | Chung, Yoo Seung | - |
dc.contributor.author | Lee, Kyu Eun | - |
dc.contributor.author | Kim, Hoon Yub | - |
dc.contributor.author | Choe, Jun-Ho | - |
dc.contributor.author | Koh, Suck Hwan | - |
dc.contributor.author | Youn, Yeo-Kyu | - |
dc.date.accessioned | 2021-09-08T06:06:37Z | - |
dc.date.available | 2021-09-08T06:06:37Z | - |
dc.date.created | 2021-06-11 | - |
dc.date.issued | 2010-01 | - |
dc.identifier.issn | 1015-9584 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/117260 | - |
dc.description.abstract | OBJECTIVE: A number of researchers have suggested the use of sodium hyaluronate carboxymethyl cellulose (HA-CMC) membrane for preventing postoperative adhesion. This study evaluated the anti-adhesive effect and safety of a newly developed HA-CMC solution in thyroidectomy. METHODS: Seventy-four patients who underwent thyroidectomy were prospectively randomized. In the study group of 38 patients, 5 mL HA-CMC solution was applied to the operative field after thyroidectomy. The subjects were asked about adhesive symptoms using a four-item questionnaire at 2 weeks, 2 months and 6 months after surgery. In addition, three items on the appearance of neck wrinkles and scars were evaluated by a physician. Each item was scored from 0 to 10. RESULTS: The mean ( standard deviation) total adhesion score at each visit was 15.22 +/- 8.99, 10.42 +/- 8.41, and 7.24 +/- 5.83 for the control group and 19.29 +/- 9.71, 9.46 +/- 5.71, and 6.03 +/- 4.32 for the study group. Total adhesion scores for both groups decreased with time (p<0.001), but no significant differences were noted between the two groups (p>0.066). There were no complications related to the HA-CMC solution. CONCLUSION: The HA-CMC solution did not decrease subjective or objective postoperative adhesion in patients undergoing thyroid surgery, although it was biologically safe. [Asian J Surg 2010;33(425-30] | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SINGAPORE PTE LTD | - |
dc.subject | ADHESION PREVENTION | - |
dc.subject | FOLLICULAR CARCINOMA | - |
dc.subject | PAPILLARY CARCINOMA | - |
dc.subject | PARATHYROID SURGERY | - |
dc.subject | BARRIER | - |
dc.subject | MULTICENTER | - |
dc.subject | SEPRAFILM | - |
dc.subject | MEMBRANE | - |
dc.subject | GLAND | - |
dc.subject | RAT | - |
dc.title | Anti-adhesive Effect and Safety of Sodium Hyaluronate and Sodium Carboxymethyl Cellulose Solution in Thyroid Surgery | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Hoon Yub | - |
dc.identifier.scopusid | 2-s2.0-77953162603 | - |
dc.identifier.wosid | 000278409400005 | - |
dc.identifier.bibliographicCitation | ASIAN JOURNAL OF SURGERY, v.33, no.1, pp.25 - 30 | - |
dc.relation.isPartOf | ASIAN JOURNAL OF SURGERY | - |
dc.citation.title | ASIAN JOURNAL OF SURGERY | - |
dc.citation.volume | 33 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 25 | - |
dc.citation.endPage | 30 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | ADHESION PREVENTION | - |
dc.subject.keywordPlus | FOLLICULAR CARCINOMA | - |
dc.subject.keywordPlus | PAPILLARY CARCINOMA | - |
dc.subject.keywordPlus | PARATHYROID SURGERY | - |
dc.subject.keywordPlus | BARRIER | - |
dc.subject.keywordPlus | MULTICENTER | - |
dc.subject.keywordPlus | SEPRAFILM | - |
dc.subject.keywordPlus | MEMBRANE | - |
dc.subject.keywordPlus | GLAND | - |
dc.subject.keywordPlus | RAT | - |
dc.subject.keywordAuthor | anti-adhesive agents | - |
dc.subject.keywordAuthor | postoperative adhesion | - |
dc.subject.keywordAuthor | sodium hyaluronate carboxymethyl cellulose | - |
dc.subject.keywordAuthor | thyroidectomy | - |
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