A bioactive coating of a silica xerogel/chitosan hybrid on titanium by a room temperature sol-gel process
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jun, Shin-Hee | - |
dc.contributor.author | Lee, Eun-Jung | - |
dc.contributor.author | Yook, Se-Won | - |
dc.contributor.author | Kim, Hyoun-Ee | - |
dc.contributor.author | Kim, Hae-Won | - |
dc.contributor.author | Koh, Young-Hag | - |
dc.date.accessioned | 2021-09-08T06:08:09Z | - |
dc.date.available | 2021-09-08T06:08:09Z | - |
dc.date.created | 2021-06-11 | - |
dc.date.issued | 2010-01 | - |
dc.identifier.issn | 1742-7061 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/117269 | - |
dc.description.abstract | A bioactive coating consisting of a silica xerogel/chitosan hybrid was applied to Ti at room temperature as a novel surface treatment for metallic implants. A crack-free thin layer (<2 mu m) was coated on Ti with a chitosan content of >30 vol.% through a sol-gel process. The coating layer became more hydrophilic with increasing silica xerogel content, as assessed by contact angle measurement. The hybrid coatings afforded excellent bone bioactivity by inducing the rapid precipitation of apatite on their surface when immersed in a simulated body fluid (SBF). Osteoblastic cells cultured on the hybrid coatings were more viable than those on a pure chitosan coating. Furthermore, the alkaline phosphate activity of the cells was significantly higher on the hybrid coatings than on a pure chitosan coating, with the highest level being achieved on the hybrid coating containing 30% chitosan. These results indicate that silica xerogel/chitosan hybrids are potentially useful as room temperature bioactive coating materials on titanium-based medical implants. (C) 2009 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.subject | GUIDED BONE REGENERATION | - |
dc.subject | TI-BASED IMPLANTS | - |
dc.subject | IN-VITRO | - |
dc.subject | CONTROLLED-RELEASE | - |
dc.subject | GLASS COATINGS | - |
dc.subject | HYDROXYAPATITE | - |
dc.subject | PHOSPHATE | - |
dc.subject | CHITOSAN | - |
dc.subject | MEMBRANE | - |
dc.subject | BIOGLASS(R) | - |
dc.title | A bioactive coating of a silica xerogel/chitosan hybrid on titanium by a room temperature sol-gel process | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Koh, Young-Hag | - |
dc.identifier.doi | 10.1016/j.actbio.2009.06.024 | - |
dc.identifier.scopusid | 2-s2.0-70449706304 | - |
dc.identifier.wosid | 000273087900035 | - |
dc.identifier.bibliographicCitation | ACTA BIOMATERIALIA, v.6, no.1, pp.302 - 307 | - |
dc.relation.isPartOf | ACTA BIOMATERIALIA | - |
dc.citation.title | ACTA BIOMATERIALIA | - |
dc.citation.volume | 6 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 302 | - |
dc.citation.endPage | 307 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.subject.keywordPlus | GUIDED BONE REGENERATION | - |
dc.subject.keywordPlus | TI-BASED IMPLANTS | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | CONTROLLED-RELEASE | - |
dc.subject.keywordPlus | GLASS COATINGS | - |
dc.subject.keywordPlus | HYDROXYAPATITE | - |
dc.subject.keywordPlus | PHOSPHATE | - |
dc.subject.keywordPlus | CHITOSAN | - |
dc.subject.keywordPlus | MEMBRANE | - |
dc.subject.keywordPlus | BIOGLASS(R) | - |
dc.subject.keywordAuthor | Silica xerogel | - |
dc.subject.keywordAuthor | Chitosan | - |
dc.subject.keywordAuthor | Hybrid | - |
dc.subject.keywordAuthor | Coating | - |
dc.subject.keywordAuthor | Bioactivity | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.