The Biological Monitoring of Urinary 1-hydroxypyrene by PAH Exposure Among Smokers
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, K. H. | - |
dc.contributor.author | Byeon, S. H. | - |
dc.date.accessioned | 2021-09-08T09:52:10Z | - |
dc.date.available | 2021-09-08T09:52:10Z | - |
dc.date.created | 2021-06-11 | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1735-6865 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/118508 | - |
dc.description.abstract | This study examines changes in the urinary 1-hydroxypyrene (1-OHP) concentration as a polycyclic aromatic hydrocarbon (PAH) metabolite related to smoking among eight volunteers. The study subjects consisted of 8 participants (2 smokers, 4 ex-smokers and 2 non-smokers; mean age 23, range 21 24 years old) in a smoking cessation program. Three urine samples were collected each week for 4 weeks from each participant to give a total of 96 urine samples. None of the participants smoked during the study period. Levels of urinary 1-OHP, as an internal dose marker of smoke containing PAHs, were measured by high performance liquid chromatography (HPLC) fluorescence detector. Urinary 1-OHP levels in the ex-smokers were decreased during the 4 weeks study period, due to ambient sources of PAH exposure. Thus, smoking cessation was only expected to result in reduction of urinary 1-OHP. Urinary 1-OHP levels were significantly correlated with the amounts of cigarettes smoked, as assessed by the questionnaire (Spearman's correlation coefficient, r=0.23, P=0.03). This study suggested that urinary 1-OHP can be a potentially useful biomarker of smoke. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER INTERNATIONAL PUBLISHING AG | - |
dc.subject | POLYCYCLIC AROMATIC-HYDROCARBONS | - |
dc.subject | CIGARETTE-SMOKING | - |
dc.subject | LUNG-CANCER | - |
dc.subject | BIOMARKER | - |
dc.subject | CARCINOGEN | - |
dc.subject | WORKERS | - |
dc.title | The Biological Monitoring of Urinary 1-hydroxypyrene by PAH Exposure Among Smokers | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Byeon, S. H. | - |
dc.identifier.scopusid | 2-s2.0-77955495913 | - |
dc.identifier.wosid | 000279971400008 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH, v.4, no.3, pp.439 - 442 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH | - |
dc.citation.title | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH | - |
dc.citation.volume | 4 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 439 | - |
dc.citation.endPage | 442 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.subject.keywordPlus | POLYCYCLIC AROMATIC-HYDROCARBONS | - |
dc.subject.keywordPlus | CIGARETTE-SMOKING | - |
dc.subject.keywordPlus | LUNG-CANCER | - |
dc.subject.keywordPlus | BIOMARKER | - |
dc.subject.keywordPlus | CARCINOGEN | - |
dc.subject.keywordPlus | WORKERS | - |
dc.subject.keywordAuthor | Biomarker | - |
dc.subject.keywordAuthor | Polycyclic aromatic hydrocarbons | - |
dc.subject.keywordAuthor | 1-hydroxypyrene | - |
dc.subject.keywordAuthor | Cigarette smoking | - |
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