Association between Tryptophan Hydroxylase 2 Polymorphism and Anger-Related Personality Traits among Young Korean Women
DC Field | Value | Language |
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dc.contributor.author | Yang, Jaewon | - |
dc.contributor.author | Lee, Moon-Soo | - |
dc.contributor.author | Lee, So-Hee | - |
dc.contributor.author | Lee, Boung-Chul | - |
dc.contributor.author | Kim, Seung-Hyun | - |
dc.contributor.author | Joe, Sook-Haeng | - |
dc.contributor.author | Jung, In-Kwa | - |
dc.contributor.author | Choi, Ihn-Geun | - |
dc.contributor.author | Ham, Byung-Joo | - |
dc.date.accessioned | 2021-09-08T10:29:14Z | - |
dc.date.available | 2021-09-08T10:29:14Z | - |
dc.date.created | 2021-06-11 | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0302-282X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/118686 | - |
dc.description.abstract | Background/Aims: It has been suggested that the serotonergic systems are associated with anger and aggressive behaviors. We investigated the association between several single nucleotide polymorphisms in the serotonergic genes and anger-related personality traits. Methods: A total of 228 healthy female Korean women participated in this study. All subjects were assessed with the State-Trait Anger Expression Inventory (STAXI) and were genotyped for 3 polymorphisms: serotonin transporter (5-HTT) gene-linked polymorphic region (5-HTTLPR), tryptophan hydroxylase 1 (TPH1) A218C, and TPH2 G-703T. Results: The Anger Expression-Out (AX-Out) subscale scores of the STAXI differed significantly between the genotypes for the TPH2 G-703T polymorphism (F = 4.825, p = 0.009). G/G homozygous subjects scored significantly higher on the AX-Out subscale than those with the G/T genotype. However, no significant differences were observed in the relationships between the STAXI subscale scores of subjects with other polymorphisms. Conclusions: This study suggests that the TPH2 G-703T polymorphism might contribute to anger-related traits, especially to the expression of anger. Copyright (C) 2010 S. Karger AG, Basel | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KARGER | - |
dc.subject | SEROTONIN TRANSPORTER GENE | - |
dc.subject | SUICIDAL-BEHAVIOR | - |
dc.subject | FUNCTIONAL POLYMORPHISM | - |
dc.subject | PROMOTER POLYMORPHISM | - |
dc.subject | MONOAMINE-OXIDASE | - |
dc.subject | REGULATORY REGION | - |
dc.subject | BIPOLAR DISORDER | - |
dc.subject | TPH GENE | - |
dc.subject | METAANALYSIS | - |
dc.subject | AGGRESSION | - |
dc.title | Association between Tryptophan Hydroxylase 2 Polymorphism and Anger-Related Personality Traits among Young Korean Women | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yang, Jaewon | - |
dc.contributor.affiliatedAuthor | Lee, Moon-Soo | - |
dc.contributor.affiliatedAuthor | Jung, In-Kwa | - |
dc.contributor.affiliatedAuthor | Ham, Byung-Joo | - |
dc.identifier.doi | 10.1159/000318572 | - |
dc.identifier.scopusid | 2-s2.0-77954396429 | - |
dc.identifier.wosid | 000280228500003 | - |
dc.identifier.bibliographicCitation | NEUROPSYCHOBIOLOGY, v.62, no.3, pp.158 - 163 | - |
dc.relation.isPartOf | NEUROPSYCHOBIOLOGY | - |
dc.citation.title | NEUROPSYCHOBIOLOGY | - |
dc.citation.volume | 62 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 158 | - |
dc.citation.endPage | 163 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Psychiatry | - |
dc.relation.journalResearchArea | Psychology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.relation.journalWebOfScienceCategory | Psychiatry | - |
dc.relation.journalWebOfScienceCategory | Psychology | - |
dc.subject.keywordPlus | SEROTONIN TRANSPORTER GENE | - |
dc.subject.keywordPlus | SUICIDAL-BEHAVIOR | - |
dc.subject.keywordPlus | FUNCTIONAL POLYMORPHISM | - |
dc.subject.keywordPlus | PROMOTER POLYMORPHISM | - |
dc.subject.keywordPlus | MONOAMINE-OXIDASE | - |
dc.subject.keywordPlus | REGULATORY REGION | - |
dc.subject.keywordPlus | BIPOLAR DISORDER | - |
dc.subject.keywordPlus | TPH GENE | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | AGGRESSION | - |
dc.subject.keywordAuthor | Anger | - |
dc.subject.keywordAuthor | Tryptophan hydroxylase 2 | - |
dc.subject.keywordAuthor | Polymorphism | - |
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