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Clinical Effects of Hypertension on the Mortality of Patients with Acute Myocardial Infarction

Authors
Kong, Dong GooJeong, Myung HoAhn, YongkeunChae, Shung ChullHur, Seung HoHong, Taek JongKim, Young JoSeong, In WhanChae, Jei KeonRhew, Jay YoungChae, In HoCho, Myeong ChanBae, Jang HoRha, Seung WoonKim, Chong JinJang, Yang SooYoon, JunghanSeung, Ki BaePark, Seung Jung
Issue Date
10월-2009
Publisher
KOREAN ACAD MEDICAL SCIENCES
Keywords
Hypertension; Myocardial infarction; Mortality
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.24, no.5, pp.800 - 806
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
Volume
24
Number
5
Start Page
800
End Page
806
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/119200
DOI
10.3346/jkms.2009.24.5.800
ISSN
1011-8934
Abstract
The incidence of ischemic heart disease has been increased rapidly in Korea. However, the clinical effects of antecedent hypertension on acute myocardial infarction have not been identified. We assessed the relationship between antecedent hypertension and clinical outcomes in 7,784 patients with acute myocardial infarction in the Korea Acute Myocardial Infarction Registry during one-year follow-up. Diabetes mellitus, hyperlipidemia, cerebrovascular disease, heart failure, and peripheral artery disease were more prevalent in hypertensives (n=3,775) than nonhypertensives (n=4,009). During hospitalization, hypertensive patients suffered from acute renal failure, shock, and cerebrovascular event more frequently than in nonhypertensives. During follow-up of one-year, the incidence of major adverse cardiac events was higher in hypertensives. In multi-variate adjustment, old age, Killip class >= III, left ventricular ejection fraction <45%, systolic blood pressure <90 mmHg on admission, post procedural TIMI flow grade <= 2, female sex, and history of hypertension were independent predictors for in-hospital mortality. However antecedent hypertension was not significantly associated with one-year mortality. Hypertension at the time of acute myocardial infarction is associated with an increased rate of in-hospital mortality.
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