Clinical Features and Prognosis of Spontaneous Bacterial Peritonitis in Korean Patients with Liver Cirrhosis: A Multicenter Retrospective Study
DC Field | Value | Language |
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dc.contributor.author | Heo, Jeong | - |
dc.contributor.author | Seo, Yeon Seok | - |
dc.contributor.author | Yim, Hyung Joon | - |
dc.contributor.author | Hahn, Taeho | - |
dc.contributor.author | Park, Sang Hoon | - |
dc.contributor.author | Ahn, Sang Hoon | - |
dc.contributor.author | Park, Jun Yong | - |
dc.contributor.author | Park, Ji Young | - |
dc.contributor.author | Kim, Moon Young | - |
dc.contributor.author | Park, Sung Keun | - |
dc.contributor.author | Cho, Mong | - |
dc.contributor.author | Um, Soon Ho | - |
dc.contributor.author | Han, Kwang Hyub | - |
dc.contributor.author | Kim, Hong Soo | - |
dc.contributor.author | Baik, Soon Koo | - |
dc.contributor.author | Kim, Byung Ik | - |
dc.contributor.author | Cho, Se Hyun | - |
dc.date.accessioned | 2021-09-08T13:44:18Z | - |
dc.date.available | 2021-09-08T13:44:18Z | - |
dc.date.created | 2021-06-11 | - |
dc.date.issued | 2009-09 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/119348 | - |
dc.description.abstract | Background/Aims: Although early recognition and treatment with effective antibiotics have lead to improvements in the prognosis of patients with spontaneous bacterial peritonitis (SBP), it remains to be a serious complication in cirrhotic patients. This study was designed to evaluate the clinical manifestations and prognosis of patients with liver cirrhosis and SBP in Korea. Methods: This was a multicenter retrospective study examining 157 episodes of SBP in 145 patients with cirrhosis. SBP was diagnosed based on a polymorphonuclear cell count in ascitic fluid of >250 cells/mm(3) in the absence of data compatible with secondary peritonitis. Results: The mean age of the cohort was 56 years, and 121 (77%) of the 157 episodes of SBP occurred in men. Microorganisms were isolated in 66 episodes (42%): Gram-negative bacteria in 54 (81.8%), Gram-positive in 11 (16.7%), and Candida in 1. Isolated Gram-negative organisms were resistant to third-gene ration cephalosporin in 6 cases (17%), to ciprofloxacin in 11 (20.8%), and to penicillin in 33 (62.3%). The treatment failure and in-hospital mortality rates were 12.1% and 21%, respectively. A high Model of End-Stage Liver Disease (MELD) score, SBP caused by extended-spectrum beta-lactamase-producing organisms, and hepatocellular carcinoma were independent prognostic factors of high in-hospital mortality. Conclusions: SBP remains to be a serious complication with high in-hospital mortality, especially in patients with a high MELD score. (Gut and Liver 2009;3:197-204) | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | EDITORIAL OFFICE GUT & LIVER | - |
dc.subject | GRAM-POSITIVE BACTERIA | - |
dc.subject | ASCITIC FLUID | - |
dc.subject | PREDICTIVE FACTORS | - |
dc.subject | NORFLOXACIN PROPHYLAXIS | - |
dc.subject | ENTERIC ORGANISMS | - |
dc.subject | RENAL IMPAIRMENT | - |
dc.subject | RANDOMIZED-TRIAL | - |
dc.subject | DOUBLE-BLIND | - |
dc.subject | INFECTIONS | - |
dc.subject | TRANSLOCATION | - |
dc.title | Clinical Features and Prognosis of Spontaneous Bacterial Peritonitis in Korean Patients with Liver Cirrhosis: A Multicenter Retrospective Study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Seo, Yeon Seok | - |
dc.contributor.affiliatedAuthor | Yim, Hyung Joon | - |
dc.contributor.affiliatedAuthor | Um, Soon Ho | - |
dc.identifier.doi | 10.5009/gnl.2009.3.3.197 | - |
dc.identifier.scopusid | 2-s2.0-70349319567 | - |
dc.identifier.wosid | 000269786700007 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, v.3, no.3, pp.197 - 204 | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.citation.title | GUT AND LIVER | - |
dc.citation.volume | 3 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 197 | - |
dc.citation.endPage | 204 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001570286 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.description.journalRegisteredClass | other | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | GRAM-POSITIVE BACTERIA | - |
dc.subject.keywordPlus | ASCITIC FLUID | - |
dc.subject.keywordPlus | PREDICTIVE FACTORS | - |
dc.subject.keywordPlus | NORFLOXACIN PROPHYLAXIS | - |
dc.subject.keywordPlus | ENTERIC ORGANISMS | - |
dc.subject.keywordPlus | RENAL IMPAIRMENT | - |
dc.subject.keywordPlus | RANDOMIZED-TRIAL | - |
dc.subject.keywordPlus | DOUBLE-BLIND | - |
dc.subject.keywordPlus | INFECTIONS | - |
dc.subject.keywordPlus | TRANSLOCATION | - |
dc.subject.keywordAuthor | Liver cirrhosis | - |
dc.subject.keywordAuthor | Peritonitis | - |
dc.subject.keywordAuthor | Prognosis | - |
dc.subject.keywordAuthor | Resistance | - |
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