Neurosteroid biosynthesis: Enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides
DC Field | Value | Language |
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dc.contributor.author | Do Rego, Jean Luc | - |
dc.contributor.author | Seong, Jae Young | - |
dc.contributor.author | Burel, Delphine | - |
dc.contributor.author | Leprince, Jerome | - |
dc.contributor.author | Luu-The, Van | - |
dc.contributor.author | Tsutsui, Kazuyoshi | - |
dc.contributor.author | Tonon, Marie-Christine | - |
dc.contributor.author | Pelletier, Georges | - |
dc.contributor.author | Vaudry, Hubert | - |
dc.date.accessioned | 2021-09-08T15:00:04Z | - |
dc.date.available | 2021-09-08T15:00:04Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2009-08 | - |
dc.identifier.issn | 0091-3022 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/119527 | - |
dc.description.abstract | Neuroactive steroids synthesized in neuronal tissue. referred to as neurosteroids, are implicated in proliferation, differentiation, activity and survival of nerve cells. Neurosteroids are also involved in the control of a number of behavioral, neuroendocrine and metabolic processes such as regulation of food intake, locomotor activity, sexual activity, aggressiveness, anxiety. depression, body temperature and blood pressure. In this article, we summarize the current knowledge regarding the existence, neuroanatomical distribution and biological activity of the enzymes responsible for the biosynthesis of neurosteroids in the brain of vertebrates, and we review the neuronal mechanisms that control the activity of these enzymes. The observation that the activity of key steroidogenic enzymes is finely tuned by various neurotransmitters and neuropeptides Strongly suggests that some of the central effects of these neuro-modulators may be mediated via the regulation of neurosteroid production. (C) 2009 Elsevier Inc. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ACADEMIC PRESS INC ELSEVIER SCIENCE | - |
dc.subject | DIAZEPAM-BINDING INHIBITOR | - |
dc.subject | AROMATASE MESSENGER-RNA | - |
dc.subject | CENTRAL-NERVOUS-SYSTEM | - |
dc.subject | SIDE-CHAIN CLEAVAGE | - |
dc.subject | GAMMA-AMINOBUTYRIC-ACID | - |
dc.subject | LATERAL SEPTAL VASOPRESSIN | - |
dc.subject | Y-LIKE IMMUNOREACTIVITY | - |
dc.subject | METHYL-D-ASPARTATE | - |
dc.subject | VASOACTIVE INTESTINAL POLYPEPTIDE | - |
dc.subject | BETA-HYDROXYSTEROID DEHYDROGENASE | - |
dc.title | Neurosteroid biosynthesis: Enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Seong, Jae Young | - |
dc.identifier.doi | 10.1016/j.yfrne.2009.05.006 | - |
dc.identifier.scopusid | 2-s2.0-67849097168 | - |
dc.identifier.wosid | 000268832600001 | - |
dc.identifier.bibliographicCitation | FRONTIERS IN NEUROENDOCRINOLOGY, v.30, no.3, pp.259 - 301 | - |
dc.relation.isPartOf | FRONTIERS IN NEUROENDOCRINOLOGY | - |
dc.citation.title | FRONTIERS IN NEUROENDOCRINOLOGY | - |
dc.citation.volume | 30 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 259 | - |
dc.citation.endPage | 301 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | DIAZEPAM-BINDING INHIBITOR | - |
dc.subject.keywordPlus | AROMATASE MESSENGER-RNA | - |
dc.subject.keywordPlus | CENTRAL-NERVOUS-SYSTEM | - |
dc.subject.keywordPlus | SIDE-CHAIN CLEAVAGE | - |
dc.subject.keywordPlus | GAMMA-AMINOBUTYRIC-ACID | - |
dc.subject.keywordPlus | LATERAL SEPTAL VASOPRESSIN | - |
dc.subject.keywordPlus | Y-LIKE IMMUNOREACTIVITY | - |
dc.subject.keywordPlus | METHYL-D-ASPARTATE | - |
dc.subject.keywordPlus | VASOACTIVE INTESTINAL POLYPEPTIDE | - |
dc.subject.keywordPlus | BETA-HYDROXYSTEROID DEHYDROGENASE | - |
dc.subject.keywordAuthor | Neurosteroids | - |
dc.subject.keywordAuthor | Central nervous system | - |
dc.subject.keywordAuthor | Steroidogenic enzymes | - |
dc.subject.keywordAuthor | Neuroanatomical distribution | - |
dc.subject.keywordAuthor | Biological activities | - |
dc.subject.keywordAuthor | Regulation | - |
dc.subject.keywordAuthor | Neurotransmitters | - |
dc.subject.keywordAuthor | Neuropeptides | - |
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