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Bioactive triterpenoids from Callistemon lanceolatus

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dc.contributor.authorJeong, Wonsik-
dc.contributor.authorHong, Seong Su-
dc.contributor.authorKim, Nahyun-
dc.contributor.authorYang, Young Taek-
dc.contributor.authorShin, Yu Su-
dc.contributor.authorLee, Chul-
dc.contributor.authorHwang, Bang Yeon-
dc.contributor.authorLee, Dongho-
dc.date.accessioned2021-09-08T16:38:01Z-
dc.date.available2021-09-08T16:38:01Z-
dc.date.created2021-06-10-
dc.date.issued2009-06-
dc.identifier.issn0253-6269-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/119965-
dc.description.abstractA new triterpenoid, 30-hydroxyalphitolic acid 1, and eight known triterpenoids, alphitolic acid 2, lupenol 3, 3-acetoxy-olean-18-en-28-oic acid 4, betulinic acid 5, ursolic acid 6, betulinic acid 3-O-caffeate 7, morolic acid 3-O-caffeate 8, and ursolic acid 3-O-caffeate 9, were isolated from Callistemon lanceolatus. Their structures were determined using spectroscopic techniques, which included 1D- and 2D-NMR. All compounds were evaluated for the inhibition of LPS-induced nitric oxide production in murine macrophage RAW264.7 cells. Betulinic acid 3-O-caffeate 7 showed a moderate inhibitory effect on nitric oxide production with IC50 value of 15.4 mu M.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherPHARMACEUTICAL SOC KOREA-
dc.subjectNITRIC-OXIDE-
dc.subjectLEAVES-
dc.subjectCONSTITUENTS-
dc.subjectDERIVATIVES-
dc.subjectCELLS-
dc.subjectACID-
dc.subjectH-1-
dc.titleBioactive triterpenoids from Callistemon lanceolatus-
dc.typeArticle-
dc.contributor.affiliatedAuthorLee, Dongho-
dc.identifier.doi10.1007/s12272-009-1605-3-
dc.identifier.scopusid2-s2.0-68149160163-
dc.identifier.wosid000267390300006-
dc.identifier.bibliographicCitationARCHIVES OF PHARMACAL RESEARCH, v.32, no.6, pp.845 - 849-
dc.relation.isPartOfARCHIVES OF PHARMACAL RESEARCH-
dc.citation.titleARCHIVES OF PHARMACAL RESEARCH-
dc.citation.volume32-
dc.citation.number6-
dc.citation.startPage845-
dc.citation.endPage849-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.identifier.kciidART001348844-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.description.journalRegisteredClasskci-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.subject.keywordPlusNITRIC-OXIDE-
dc.subject.keywordPlusLEAVES-
dc.subject.keywordPlusCONSTITUENTS-
dc.subject.keywordPlusDERIVATIVES-
dc.subject.keywordPlusCELLS-
dc.subject.keywordPlusACID-
dc.subject.keywordPlusH-1-
dc.subject.keywordAuthorCallistemon lanceolatus-
dc.subject.keywordAuthorMyrtaceae-
dc.subject.keywordAuthorTriterpenoids-
dc.subject.keywordAuthorBetulinic acid 3-O-caffeate-
dc.subject.keywordAuthorNO production inhibitor-
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