Potential Benefit of Intraocular Pressure Reduction in Normal-Tension Glaucoma in South Korea
DC Field | Value | Language |
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dc.contributor.author | Seong, Gong Je | - |
dc.contributor.author | Rho, Sae Heun | - |
dc.contributor.author | Kim, Chang Sik | - |
dc.contributor.author | Il Moon, Jong | - |
dc.contributor.author | Kook, Michael Scott | - |
dc.contributor.author | Kim, Yong Yeon | - |
dc.contributor.author | Ma, Kyoung Tak | - |
dc.contributor.author | Hong, Young Jae | - |
dc.contributor.author | Nelson, Lindsay A. | - |
dc.contributor.author | Kruft, Bonnie | - |
dc.contributor.author | Stewart, Jeanette A. | - |
dc.contributor.author | Stewart, William C. | - |
dc.date.accessioned | 2021-09-08T20:06:29Z | - |
dc.date.available | 2021-09-08T20:06:29Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2009-02 | - |
dc.identifier.issn | 1080-7683 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/120628 | - |
dc.description.abstract | Purpose: The aim of this study was to evaluate the potential benefit of intraocular pressure (IOP) reduction in normaltension glaucoma (NTG) Asian adult patients in South Korea. Methods: This was a retrospective, multicenter analysis of 166 NTG Asian adult patients in South Korea. The patient population consisted of Korean patients with NTG with at least 5 years of records available for evaluation. Patients all had typical glaucomatous optic-disc and/or visual-field changes but had never had a recorded IOP >21 mmHg. Results: Overall, 48 (29%) patients were progressed and 116 (71%) were stable over the follow-up period. Of patients with IOPs <= 14mmHg (21/93), 23% progressed and <= 15mmHg (27/73) 37% progressed (P = 0.041). The mean IOP for the stable group was 14.0 +/- 1.8 mmHg, whereas with the progressed group the average mean IOP was 14.4 +/- 1.6 mmHg (P = 0.20). The mean peak IOP was 17.4 +/- 2.2 mmHg in the stable group and 17.8 +/- 2.0 mmHg in the progressed group (P = 0.26). Multivariate linear regression analysis did not any identify independent risk factors for progression, including age, gender, or mean and peak IOP. Conclusions: This study provides initial evidence that Korean patients with normal-tension glaucoma, treated to lower IOPs, may have a decreased incidence of progression over 5 years than those patients with higher IOPs. More research is required to confirm this finding. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MARY ANN LIEBERT, INC | - |
dc.subject | OPEN-ANGLE GLAUCOMA | - |
dc.subject | LONG-TERM PROGRESSION | - |
dc.subject | CORNEAL THICKNESS | - |
dc.subject | JAPANESE POPULATION | - |
dc.subject | OPTINEURIN GENE | - |
dc.subject | VISUAL-LOSS | - |
dc.subject | ASSOCIATION | - |
dc.subject | STABILITY | - |
dc.title | Potential Benefit of Intraocular Pressure Reduction in Normal-Tension Glaucoma in South Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Yong Yeon | - |
dc.identifier.doi | 10.1089/jop.2008.0056 | - |
dc.identifier.scopusid | 2-s2.0-61749084977 | - |
dc.identifier.wosid | 000264197500012 | - |
dc.identifier.bibliographicCitation | JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, v.25, no.1, pp.91 - 96 | - |
dc.relation.isPartOf | JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS | - |
dc.citation.title | JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS | - |
dc.citation.volume | 25 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 91 | - |
dc.citation.endPage | 96 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Ophthalmology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Ophthalmology | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | OPEN-ANGLE GLAUCOMA | - |
dc.subject.keywordPlus | LONG-TERM PROGRESSION | - |
dc.subject.keywordPlus | CORNEAL THICKNESS | - |
dc.subject.keywordPlus | JAPANESE POPULATION | - |
dc.subject.keywordPlus | OPTINEURIN GENE | - |
dc.subject.keywordPlus | VISUAL-LOSS | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | STABILITY | - |
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