The Effects of Midazolam on the Bispectral Index after Fetal Expulsion in Caesarean Section under General Anaesthesia with Sevoflurane
- Authors
- Ok, S-J; Kim, W-Y; Lee, Y-S; Kim, K-G; Shin, H-W; Chang, M-S; Kim, J-H; Park, Y-C
- Issue Date
- 1월-2009
- Publisher
- SAGE PUBLICATIONS LTD
- Keywords
- MIDAZOLAM; SEVOFLURANE; CAESAREAN SECTION; FETAL EXPULSION; BISPECTRAL INDEX
- Citation
- JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, v.37, no.1, pp.154 - 162
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- Volume
- 37
- Number
- 1
- Start Page
- 154
- End Page
- 162
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/120868
- DOI
- 10.1177/147323000903700118
- ISSN
- 0300-0605
- Abstract
- The effects of midozolam used with low concentration inhaled anaesthetics on the bispectral index (BIS) was investigated after fetal expulsion during caesarean section. Forty-five patients undergoing caesarean section received either normal saline (control, n = 15), or an intravenous bolus of 0.03 mg/kg (n = 15) or 0.05 mg/kg (n = 15) midazolam. Changes in BIS and maternal haemodynamics were monitored before induction, on intubation, at uterine incision, on delivery, at 3, 5 and 10 min after fetal expulsion, at subcutaneous tissue closure, at skin closure, on eye opening and at extubation. BIS values in the group that received 0.05 mg/kg midazolam were significantly lower than in the other two groups at 3, 5 and 10 min after fetal expulsion, and at subcutaneous tissue closure and skin closure. Values of BIS < 60 could only be maintained with 0.05 mg/kg midazolam and there was no delay in maternal emergence or recovery.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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