저용량 브로모크립틴 치료로 반복적인 정상 임신과 종양 감퇴를 보인 거대프로락틴선종 1예Normal Repetitive Pregnancies and Tumor Regression Induced by Low-Dose Bromocriptine in a Patient with Macroprolactinoma
- Other Titles
- Normal Repetitive Pregnancies and Tumor Regression Induced by Low-Dose Bromocriptine in a Patient with Macroprolactinoma
- Authors
- 최혜정; 박진용; 김희영; 서지아; 김신곤; 김난희; 최경묵; 백세현; 최동섭; 최우석; 송종규
- Issue Date
- 2009
- Publisher
- 대한내분비학회
- Keywords
- Bromocriptine; macroprolactinoma; pregnancy
- Citation
- Endocrinology and Metabolism, v.24, no.1, pp.42 - 46
- Indexed
- KCI
- Journal Title
- Endocrinology and Metabolism
- Volume
- 24
- Number
- 1
- Start Page
- 42
- End Page
- 46
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/121072
- ISSN
- 2093-596X
- Abstract
- Prolactin-secreting adenomas are the most common pituitary tumors. Menstrual disturbances and infertility are the main complaints in women with prolactinoma. Dopaminergic agonists such as bromocriptine are well-established treatments for prolactinoma when pregnancy is desired. Pregnancy-related outcomes in macroprolactinoma are worse than those in microprolactinoma. In addition, symptomatic tumor expansion during pregnancy occurs in 30% of women with macroprolactinoma. Therefore, when women with macroprolactinoma are planning a pregnancy, serum prolactin level should be normalized and the tumor volume significantly reduced. On the other hand, a spontaneous regression of macroprolactinoma can occur after pregnancy. We report a case of macroprolactinoma showing significant tumor regression during repeated pregnancies and low dose bromocriptine treatment, with a literature review.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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