Reversible Posterior Leukoencephalopathy Syndrome in a Patient with Relapsed Hodgkin’s Disease: A Case ReportReversible Posterior Leukoencephalopathy Syndrome in a Patient with Relapsed Hodgkin’s Disease: A Case Report
- Other Titles
- Reversible Posterior Leukoencephalopathy Syndrome in a Patient with Relapsed Hodgkin’s Disease: A Case Report
- Authors
- Jee Won Kim; Ji Mi Moon; Eun-Joo Kang; Yoon Ji Choi; Jung Sun Kim; Jong Gwon Choi; Hee Yeon Seo; 성화정; 김병수; Jun Suk Kim; 최철원; Woo-Keun Seo
- Issue Date
- 2009
- Publisher
- 대한혈액학회
- Keywords
- Posterior leukoencephalopathy syndrome; Hodgkin disease; ESHAP regimen
- Citation
- Blood Research, v.44, no.3, pp.177 - 181
- Indexed
- KCI
- Journal Title
- Blood Research
- Volume
- 44
- Number
- 3
- Start Page
- 177
- End Page
- 181
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/121342
- ISSN
- 2287-979X
- Abstract
- Reversible posterior leukoencephalopathy syndrome (RPLS) is a distinctive clinicoradiological entity that’s characterized by headache, confusion, seizure and frequent visual disturbances. It is associated with certain neuro-radiological findings, and predominantly white matter abnormalities of the parieto-occipital lobes. RPLS has been identified mostly in patients with malignant hypertension, pre-eclampsia and renal insufficiency and in those patients who are using immunosuppressive agents or cytotoxic drugs. We report here on a case of RPLS in a patient who was undergoing chemotherapy. A 49-year-old woman presented with abrupt mental changes and visual disturbances five days after the administration of a chemotherapeutic agent. MRI showed hyper-intense signals on the magnetic resonance (MR) diffusion images in the bilateral temporal, parietal and occipital lobes. The clinical manifestations completely resolved after one week of treatment that consisted of blood pressure control, a negative intake-output balance and the best supportive care. These radiological changes and the reversible clinical manifestations were consistent with RPLS.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
- Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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