궤양성 대장염의 최신치료Advances in ulcerative colitis therapy
- Other Titles
- Advances in ulcerative colitis therapy
- Authors
- 진윤태; 김주형
- Issue Date
- 2009
- Publisher
- 대한내과학회
- Keywords
- Ulcerative colitis; Therapy; Biologic agent; 궤양성 대장염; 치료; 생물학적 제제
- Citation
- 대한내과학회지, v.76, no.6, pp.654 - 660
- Indexed
- KCI
- Journal Title
- 대한내과학회지
- Volume
- 76
- Number
- 6
- Start Page
- 654
- End Page
- 660
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/121417
- ISSN
- 1738-9364
- Abstract
- Ulcerative colitis is an idiopathic inflammatory bowel disease characterized by colonic mucosal inflammation and chronic relapsing episodes. The initial therapeutic approach depends on both the extent of colonic involvement and the severity of the disease process at presentation. The mainstay of ulcerative colitis therapy is the administration of 5-aminosalicylic acid (5-ASA) or steroid. Additional medical therapy or colectomy should be considered if the patient remains symptomatic despite conventional therapy, regardless of the extent of colonic involvement. Cyclosporins are effective as a short-term rescue therapy for steroid-refractory ulcerative colitis. Recently, new 5-ASA and steroid formulations with altered delivery, dosing regimens, and less frequent administration have been introduced and demonstrated to be efficacious in active mild to moderate colitis. Infliximab is given to try to avoid the need for colectomy and has proven efficacious in ulcerative colitis. This review outlines the standard therapy for ulcerative colitis and discusses new insights into the recent trend focusing on new therapies, including biological agents and leukocytapheresis.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.