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Bioactive constituents of the stem bark of Mitrephora glabra

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dc.contributor.authorLi, C.-
dc.contributor.authorLee, D.-
dc.contributor.authorGraf, T.N.-
dc.contributor.authorPhifer, S.S.-
dc.contributor.authorNakanishi, Y.-
dc.contributor.authorRiswan, S.-
dc.contributor.authorSetyowati, F.M.-
dc.contributor.authorSaribi, A.M.-
dc.contributor.authorSoejarto, D.D.-
dc.contributor.authorFarnsworth, N.R.-
dc.contributor.authorFalkinham, III J.O.-
dc.contributor.authorKroll, D.J.-
dc.contributor.authorKinghorn, A.D.-
dc.contributor.authorWani, M.C.-
dc.contributor.authorOberlies, N.H.-
dc.date.accessioned2021-09-09T00:17:14Z-
dc.date.available2021-09-09T00:17:14Z-
dc.date.created2021-06-17-
dc.date.issued2009-
dc.identifier.issn0163-3864-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/121870-
dc.description.abstractBioactivity-guided fractionation of the stem bark of Mitrephora glabra yielded nine compounds, comprising three entkaurenoids (1-3), five polyacetylenic acids/esters (4-8), and one aporphine alkaloid, liriodenine (9). The structures of the six new compounds (1-3, 5, 7, and 8) were determined by spectroscopic data interpretation. All compounds were evaluated for their inhibitory activities against a panel of cancer cell lines and a battery of microorganisms. © 2009 American Chemical Society and American Society of Pharmacognosy.-
dc.languageEnglish-
dc.language.isoen-
dc.subjectaporphine derivative-
dc.subjectliriodenine-
dc.subjectMitrephora glabra extract-
dc.subjectplant extract-
dc.subjectunclassified drug-
dc.subjectantiinfective agent-
dc.subjectantineoplastic agent-
dc.subjectaporphine derivative-
dc.subjectditerpene-
dc.subjectliriodenine-
dc.subjectpolyacetylene derivative-
dc.subjectAnnonaceae-
dc.subjectantimicrobial activity-
dc.subjectarticle-
dc.subjectbark-
dc.subjectcancer cell culture-
dc.subjectcontrolled study-
dc.subjectcytotoxicity-
dc.subjectdrug isolation-
dc.subjectheteronuclear multiple bond correlation-
dc.subjecthuman-
dc.subjecthuman cell-
dc.subjectmicroorganism-
dc.subjectMitrephora glabra-
dc.subjectnuclear magnetic resonance-
dc.subjectplant stem-
dc.subjectspectroscopy-
dc.subjectAspergillus niger-
dc.subjectchemical structure-
dc.subjectchemistry-
dc.subjectdrug effect-
dc.subjectdrug screening-
dc.subjectfemale-
dc.subjectIndonesia-
dc.subjectisolation and purification-
dc.subjectmedicinal plant-
dc.subjectmicrobiological examination-
dc.subjectMicrococcus luteus-
dc.subjectMycobacterium-
dc.subjectSaccharomyces cerevisiae-
dc.subjectMitrephora-
dc.subjectAnnonaceae-
dc.subjectAnti-Infective Agents-
dc.subjectAntineoplastic Agents, Phytogenic-
dc.subjectAporphines-
dc.subjectAspergillus niger-
dc.subjectDiterpenes-
dc.subjectDrug Screening Assays, Antitumor-
dc.subjectFemale-
dc.subjectHumans-
dc.subjectIndonesia-
dc.subjectMicrobial Sensitivity Tests-
dc.subjectMicrococcus luteus-
dc.subjectMolecular Structure-
dc.subjectMycobacterium-
dc.subjectNuclear Magnetic Resonance, Biomolecular-
dc.subjectPlant Bark-
dc.subjectPlants, Medicinal-
dc.subjectPolyacetylenes-
dc.subjectSaccharomyces cerevisiae-
dc.titleBioactive constituents of the stem bark of Mitrephora glabra-
dc.typeArticle-
dc.contributor.affiliatedAuthorLee, D.-
dc.identifier.doi10.1021/np900572g-
dc.identifier.scopusid2-s2.0-73349131425-
dc.identifier.bibliographicCitationJournal of Natural Products, v.72, no.11, pp.1949 - 1953-
dc.relation.isPartOfJournal of Natural Products-
dc.citation.titleJournal of Natural Products-
dc.citation.volume72-
dc.citation.number11-
dc.citation.startPage1949-
dc.citation.endPage1953-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscopus-
dc.subject.keywordPlusaporphine derivative-
dc.subject.keywordPlusliriodenine-
dc.subject.keywordPlusMitrephora glabra extract-
dc.subject.keywordPlusplant extract-
dc.subject.keywordPlusunclassified drug-
dc.subject.keywordPlusantiinfective agent-
dc.subject.keywordPlusantineoplastic agent-
dc.subject.keywordPlusaporphine derivative-
dc.subject.keywordPlusditerpene-
dc.subject.keywordPlusliriodenine-
dc.subject.keywordPluspolyacetylene derivative-
dc.subject.keywordPlusAnnonaceae-
dc.subject.keywordPlusantimicrobial activity-
dc.subject.keywordPlusarticle-
dc.subject.keywordPlusbark-
dc.subject.keywordPluscancer cell culture-
dc.subject.keywordPluscontrolled study-
dc.subject.keywordPluscytotoxicity-
dc.subject.keywordPlusdrug isolation-
dc.subject.keywordPlusheteronuclear multiple bond correlation-
dc.subject.keywordPlushuman-
dc.subject.keywordPlushuman cell-
dc.subject.keywordPlusmicroorganism-
dc.subject.keywordPlusMitrephora glabra-
dc.subject.keywordPlusnuclear magnetic resonance-
dc.subject.keywordPlusplant stem-
dc.subject.keywordPlusspectroscopy-
dc.subject.keywordPlusAspergillus niger-
dc.subject.keywordPluschemical structure-
dc.subject.keywordPluschemistry-
dc.subject.keywordPlusdrug effect-
dc.subject.keywordPlusdrug screening-
dc.subject.keywordPlusfemale-
dc.subject.keywordPlusIndonesia-
dc.subject.keywordPlusisolation and purification-
dc.subject.keywordPlusmedicinal plant-
dc.subject.keywordPlusmicrobiological examination-
dc.subject.keywordPlusMicrococcus luteus-
dc.subject.keywordPlusMycobacterium-
dc.subject.keywordPlusSaccharomyces cerevisiae-
dc.subject.keywordPlusMitrephora-
dc.subject.keywordPlusAnnonaceae-
dc.subject.keywordPlusAnti-Infective Agents-
dc.subject.keywordPlusAntineoplastic Agents, Phytogenic-
dc.subject.keywordPlusAporphines-
dc.subject.keywordPlusAspergillus niger-
dc.subject.keywordPlusDiterpenes-
dc.subject.keywordPlusDrug Screening Assays, Antitumor-
dc.subject.keywordPlusFemale-
dc.subject.keywordPlusHumans-
dc.subject.keywordPlusIndonesia-
dc.subject.keywordPlusMicrobial Sensitivity Tests-
dc.subject.keywordPlusMicrococcus luteus-
dc.subject.keywordPlusMolecular Structure-
dc.subject.keywordPlusMycobacterium-
dc.subject.keywordPlusNuclear Magnetic Resonance, Biomolecular-
dc.subject.keywordPlusPlant Bark-
dc.subject.keywordPlusPlants, Medicinal-
dc.subject.keywordPlusPolyacetylenes-
dc.subject.keywordPlusSaccharomyces cerevisiae-
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