The ultrastructural changes of tendon axonal profiles of medial rectus muscles according to duration in patients with intermittent exotropia
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, S-H | - |
dc.contributor.author | Cho, Y. A. | - |
dc.contributor.author | Park, C-H | - |
dc.contributor.author | Uhm, C-S | - |
dc.date.accessioned | 2021-09-09T05:46:46Z | - |
dc.date.available | 2021-09-09T05:46:46Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2008-08 | - |
dc.identifier.issn | 0950-222X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/122971 | - |
dc.description.abstract | Purpose The goal of this study was to investigate the ultrastructural changes of tendon axonal profiles of medial recti in patients with intermittent exotropia at different ages. In addition, we compared the patterns of degeneration with those of secondary exotropia over time. Methods Thirteen patients, with different ages, with exotropia who had undergone surgery were included in this study and divided into two groups. Eight patients had intermittent or constant exotropia; their age ranged from 6 to 45 years and they had exotropia since childhood without amblyopia, these patients were assigned to group A. The other five patients with sensory exotropia ranged in age from 15 to 52 years; they did not have exotropia until a visual insult and had poor vision in one eye, these patients were assigned to group B. All patients had the medial recti resected (3-5.5mm) to obtain tissue samples. All specimens were examined with an electron microscope. Results Schwann cell degeneration was observed with increased neurofilament density, axonal vacuoles and hydropic swelling of the Schwann cells in two patients less than 10 years of age in group A. The other six patients were more than 10 years of age in group A, and it was not possible to identify the tendon axonal profiles or neural structures in the medial recti specimens of these patients. For group B, all patients had intact proprioceptor structures including Schwann cells. However, the collagen diameter decreased and density increased within the capsule according to the duration of exotropia. Conclusion Schwann cell degeneration of tendon proprioceptors in the medial rectus might induce the degeneration of proprioceptors in patients with intermittent exotropia over time. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.subject | EXTRAOCULAR-MUSCLES | - |
dc.subject | CAT | - |
dc.subject | PROJECTIONS | - |
dc.subject | STRABISMUS | - |
dc.subject | AFFERENTS | - |
dc.subject | NUCLEI | - |
dc.subject | CELLS | - |
dc.title | The ultrastructural changes of tendon axonal profiles of medial rectus muscles according to duration in patients with intermittent exotropia | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, S-H | - |
dc.contributor.affiliatedAuthor | Cho, Y. A. | - |
dc.contributor.affiliatedAuthor | Uhm, C-S | - |
dc.identifier.doi | 10.1038/eye.2008.133 | - |
dc.identifier.scopusid | 2-s2.0-50449092561 | - |
dc.identifier.wosid | 000258413200017 | - |
dc.identifier.bibliographicCitation | EYE, v.22, no.8, pp.1076 - 1081 | - |
dc.relation.isPartOf | EYE | - |
dc.citation.title | EYE | - |
dc.citation.volume | 22 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1076 | - |
dc.citation.endPage | 1081 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Ophthalmology | - |
dc.relation.journalWebOfScienceCategory | Ophthalmology | - |
dc.subject.keywordPlus | EXTRAOCULAR-MUSCLES | - |
dc.subject.keywordPlus | CAT | - |
dc.subject.keywordPlus | PROJECTIONS | - |
dc.subject.keywordPlus | STRABISMUS | - |
dc.subject.keywordPlus | AFFERENTS | - |
dc.subject.keywordPlus | NUCLEI | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordAuthor | tendon axonal profiles | - |
dc.subject.keywordAuthor | proprioceptor | - |
dc.subject.keywordAuthor | Schwann cell degeneration | - |
dc.subject.keywordAuthor | intermittent exotropia | - |
dc.subject.keywordAuthor | secondary exotropia | - |
dc.subject.keywordAuthor | ultrastructural changes according to age | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.