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A polymeric microfluidic valve employing a pH-responsive hydrogel microsphere as an actuating source

Authors
Park, JYOh, HJKim, DJBaek, JYLee, SH
Issue Date
3월-2006
Publisher
IOP PUBLISHING LTD
Citation
JOURNAL OF MICROMECHANICS AND MICROENGINEERING, v.16, no.3, pp.656 - 663
Indexed
SCIE
SCOPUS
Journal Title
JOURNAL OF MICROMECHANICS AND MICROENGINEERING
Volume
16
Number
3
Start Page
656
End Page
663
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/123154
DOI
10.1088/0960-1317/16/3/022
ISSN
0960-1317
Abstract
In this paper, we propose a new fabrication method for pH-responsive microfluidic valves. Conventionally, an in. situ photopolymerization method has been employed to build the micro functional structure inside a microfluidic channel. Here, we suggest a new method that allows the mass production of a stimuli-responsive microsystem through the use of a pre-made microstructure as an actuating element, like the assembly of commercial products in a factory. We have massively fabricated pH-responsive microspheres that act as an actuating component through the use of PDMS-based microfluidic apparatus and an 'on the fly' photopolymerization method. By incorporation of this microsphere into the microvalve during the fabrication process, we have produced a pH-responsive microfluldic valve in a simple way. The operation and the function of the fabricated microvalve were evaluated through diverse experiments. The microvalve was successfully fabricated, and functioned well according to the pH change.
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