Cerebral white matter lesions and hypertension status in the elderly Korean: the Ansan Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, MK | - |
dc.contributor.author | Jo, I | - |
dc.contributor.author | Park, MH | - |
dc.contributor.author | Kim, TK | - |
dc.contributor.author | Jo, SA | - |
dc.contributor.author | Shin, C | - |
dc.date.accessioned | 2021-09-09T06:52:28Z | - |
dc.date.available | 2021-09-09T06:52:28Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2005-05 | - |
dc.identifier.issn | 0167-4943 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/123240 | - |
dc.description.abstract | There is evidence of an association of hypertension with white matter lesions (WMLs), leukoaraiosis, in the human brain in the United States, Europe and Japan. However, no study on this association has been reported in Korea. Community-dwelling elderly subjects aged over 61 years 41 were randomly selected from sample, of the Ansan Health Study, while their blood pressures (BPs) were measured using a highly standardized protocol. Hypertension was defined as a systolic BP >= 140 mmHg or a diastolic BP >= 90 mmHg or as reported treatment with hypertensive medication, and further subclassified with respect to its Subtypes and control status. WMLs were determined by a 1.5-T MRI scan and further categorized into five subgroups with respect to its severity. Hypertension status, such as uncontrolled hypertension even after anti hypertensive medication (adjusted odd ratio [OR] = 6.07; 95% CI, 2.08-17.78), isolated systolic hypertension before medication (OR = 2.66; 95% CI, 1.08-6.57), and hypertension before medication (OR = 2.55; 95% CI 1. 19-5.46) were significantly and independently correlated with the presence and severity of WMLs. Advancing, age (OR = 1.76; 95% CI, 1.38-2.25), lacunar infarction (OR = 3.19; 95% CI, 1.83-5.58), and cigarette smoking (OR = 1. 10; 95% CI 1.03-1.18) were significantly related to the presence and severity of WMLs. Regular and tight control for hypertension should be exercised to prevent WMLs among the elderly with hypertension. (c) 2004 Elsevier Ireland Ltd. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER IRELAND LTD | - |
dc.subject | VASCULAR RISK-FACTORS | - |
dc.subject | PERIVENTRICULAR LESIONS | - |
dc.subject | CARDIOVASCULAR HEALTH | - |
dc.subject | LEUKO-ARAIOSIS | - |
dc.subject | STROKE | - |
dc.subject | MRI | - |
dc.subject | ARTERIOLOSCLEROSIS | - |
dc.subject | ABNORMALITIES | - |
dc.subject | LEUKOARAIOSIS | - |
dc.subject | POPULATION | - |
dc.title | Cerebral white matter lesions and hypertension status in the elderly Korean: the Ansan Study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shin, C | - |
dc.identifier.doi | 10.1016/j.archger.2004.09.003 | - |
dc.identifier.scopusid | 2-s2.0-16244408945 | - |
dc.identifier.wosid | 000228675200005 | - |
dc.identifier.bibliographicCitation | ARCHIVES OF GERONTOLOGY AND GERIATRICS, v.40, no.3, pp.265 - 273 | - |
dc.relation.isPartOf | ARCHIVES OF GERONTOLOGY AND GERIATRICS | - |
dc.citation.title | ARCHIVES OF GERONTOLOGY AND GERIATRICS | - |
dc.citation.volume | 40 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 265 | - |
dc.citation.endPage | 273 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Geriatrics & Gerontology | - |
dc.relation.journalWebOfScienceCategory | Geriatrics & Gerontology | - |
dc.subject.keywordPlus | VASCULAR RISK-FACTORS | - |
dc.subject.keywordPlus | PERIVENTRICULAR LESIONS | - |
dc.subject.keywordPlus | CARDIOVASCULAR HEALTH | - |
dc.subject.keywordPlus | LEUKO-ARAIOSIS | - |
dc.subject.keywordPlus | STROKE | - |
dc.subject.keywordPlus | MRI | - |
dc.subject.keywordPlus | ARTERIOLOSCLEROSIS | - |
dc.subject.keywordPlus | ABNORMALITIES | - |
dc.subject.keywordPlus | LEUKOARAIOSIS | - |
dc.subject.keywordPlus | POPULATION | - |
dc.subject.keywordAuthor | cerebral white matter lesions | - |
dc.subject.keywordAuthor | leukoaraiosis | - |
dc.subject.keywordAuthor | hypertension | - |
dc.subject.keywordAuthor | Korean | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.