Protein secondary structure prediction using sequence profile and conserved domain profile
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Woo, SK | - |
dc.contributor.author | Park, CB | - |
dc.contributor.author | Lee, SW | - |
dc.date.accessioned | 2021-09-09T06:57:34Z | - |
dc.date.available | 2021-09-09T06:57:34Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0302-9743 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/123268 | - |
dc.description.abstract | In this paper, we proposed a novel method for protein secondary structure prediction using sequence profile and conserved domain profile. Sequence profile generated from PSI-BLAST (position specific iterated BLAST) has been widely used in protein secondary structure prediction, because PSI-BLAST shows good performance in finding remote homology. Conserved domains kept functional and structural information of related proteins; therefore we could draw remote homology information in conserved domains using RPS-BLAST (reverse position specific BLAST). We combined sequence profile and conserved domain profile to get more remote homology information, and propose a method which used the combined profile to predict the protein secondary structures. In order to verify the effectiveness of our proposed method, we implemented a protein secondary structure prediction system. Overall prediction accuracy reached 75.9% on the RS126 data set. The improvement by incorporating conserved domain information exceeded 3%, and this result showed that our proposed method could improve significantly the accuracy of protein secondary structure prediction. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER-VERLAG BERLIN | - |
dc.title | Protein secondary structure prediction using sequence profile and conserved domain profile | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, SW | - |
dc.identifier.wosid | 000232529000001 | - |
dc.identifier.bibliographicCitation | ADVANCES IN INTELLIGENT COMPUTING, PT 2, PROCEEDINGS, v.3645, pp.1 - 10 | - |
dc.relation.isPartOf | ADVANCES IN INTELLIGENT COMPUTING, PT 2, PROCEEDINGS | - |
dc.citation.title | ADVANCES IN INTELLIGENT COMPUTING, PT 2, PROCEEDINGS | - |
dc.citation.volume | 3645 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 10 | - |
dc.type.rims | ART | - |
dc.type.docType | Article; Proceedings Paper | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Computer Science | - |
dc.relation.journalWebOfScienceCategory | Computer Science, Artificial Intelligence | - |
dc.relation.journalWebOfScienceCategory | Computer Science, Theory & Methods | - |
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