Clinicopathologic study of 24 patients with primary cardiac sarcomas: a 10-year single institution experience
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Chul Hwan | - |
dc.contributor.author | Dancer, Jane Y. | - |
dc.contributor.author | Coffey, Donna | - |
dc.contributor.author | Zhai, Qihui J. | - |
dc.contributor.author | Reardon, Michael | - |
dc.contributor.author | Ayala, Alberto Go | - |
dc.contributor.author | Ro, Jae Y. | - |
dc.date.accessioned | 2021-09-09T07:52:34Z | - |
dc.date.available | 2021-09-09T07:52:34Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2008-06 | - |
dc.identifier.issn | 0046-8177 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/123458 | - |
dc.description.abstract | Primary cardiac sarcomas are exceptionally rare. We present a 10-year, single-institution experience with 24 primary adult cardiac sarcomas. These cases were retrieved from the Department of Pathology data file of the Methodist Hospital at Houston, TX. Clinical presentation and pathologic features were analyzed. Histologic classification was followed according to the criteria set by the World Health Organization, and grading according to the system proposed by the Federation Nationale des Centres de Lutte Contrele Cancer. There were 14 men and 10 women (male/female, 1.4:1) with a mean age of 42.2 years (range 20-68 years). The tumors involved the right atrium in 14 cases, left atrium in 6 cases, right ventricle in 2 cases, and left ventricle in 2 cases. The tumor size ranged from 2.0 to 17.0 cm (mean 7.2 cm), and, histologically, there were 10 angiosarcomas, 9 unclassified sarcomas, 3 synovial sarcomas, and 2 leiomyosarcomas. All 10 angiosarcomas originated from the right atrium, whereas 5 of the unclassified sarcomas were from the left atrium. Although cases were limited, no predilection site was found for the other histologic types. All tumors were graded as 2 (5 cases) or 3 (19 cases) in differentiation. The prognosis was poor with a median survival time of 25 months after diagnosis. The grade was not statistically significant on survival (P = .14). In conclusion, angiosarcoma and unclassified sarcomas are the most common sarcomas of the heart accounting for 76%, but rare tumors such as synovial sarcoma and leiomyosarcoma may also occur in this organ. The survival of cardiac sarcomas is poor. (C) 2008 Elsevier Inc. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | W B SAUNDERS CO-ELSEVIER INC | - |
dc.subject | MALIGNANT FIBROUS HISTIOCYTOMA | - |
dc.subject | TUMORS | - |
dc.title | Clinicopathologic study of 24 patients with primary cardiac sarcomas: a 10-year single institution experience | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Chul Hwan | - |
dc.identifier.doi | 10.1016/j.humpath.2007.12.018 | - |
dc.identifier.scopusid | 2-s2.0-44449106543 | - |
dc.identifier.wosid | 000256634200017 | - |
dc.identifier.bibliographicCitation | HUMAN PATHOLOGY, v.39, no.6, pp.933 - 938 | - |
dc.relation.isPartOf | HUMAN PATHOLOGY | - |
dc.citation.title | HUMAN PATHOLOGY | - |
dc.citation.volume | 39 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 933 | - |
dc.citation.endPage | 938 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Pathology | - |
dc.relation.journalWebOfScienceCategory | Pathology | - |
dc.subject.keywordPlus | MALIGNANT FIBROUS HISTIOCYTOMA | - |
dc.subject.keywordPlus | TUMORS | - |
dc.subject.keywordAuthor | heart | - |
dc.subject.keywordAuthor | malignant neoplasm | - |
dc.subject.keywordAuthor | sarcoma | - |
dc.subject.keywordAuthor | angiosarcoma | - |
dc.subject.keywordAuthor | unclassified sarcoma | - |
dc.subject.keywordAuthor | synovial sarcoma | - |
dc.subject.keywordAuthor | leiomyosarcoma | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.