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Hollow silica nanocontainers as drug delivery vehicles

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dc.contributor.authorYang, Jaemoon-
dc.contributor.authorLee, Jaewon-
dc.contributor.authorKang, Jinyoung-
dc.contributor.authorLee, Kwangyeol-
dc.contributor.authorSuh, Jin-Suck-
dc.contributor.authorYoon, Ho-Geun-
dc.contributor.authorHuh, Yong-Min-
dc.contributor.authorHaam, Seungjoo-
dc.date.accessioned2021-09-09T09:32:06Z-
dc.date.available2021-09-09T09:32:06Z-
dc.date.created2021-06-10-
dc.date.issued2008-04-01-
dc.identifier.issn0743-7463-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/123761-
dc.description.abstractNovel hollow silica nanoparticles (HSNPs) for drug delivery vehicles were synthesized using silica-coated magnetic assemblies, which are composed of a number of Fe3O4 nanocrystals, as templates. The core cavity was obtained by removal of Fe3O4 phase with hydrochloric acid and subsequent calcination at a high temperature. HSNPs were modified by amine in order to introduce positive surface charge and further PEGylated for increased solubility in aqueous medium. Doxorubicin as a model drug was loaded into the HSNPs, and notable sustained drug release from HSNPs was demonstrated.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherAMER CHEMICAL SOC-
dc.subjectCORE-SHELL PARTICLES-
dc.subjectNANOPARTICLES-
dc.subjectSPHERES-
dc.subjectFABRICATION-
dc.subjectRELEASE-
dc.subjectDOXORUBICIN-
dc.subjectCAPSULES-
dc.titleHollow silica nanocontainers as drug delivery vehicles-
dc.typeArticle-
dc.contributor.affiliatedAuthorLee, Kwangyeol-
dc.identifier.doi10.1021/la701688t-
dc.identifier.scopusid2-s2.0-42249094044-
dc.identifier.wosid000254480500064-
dc.identifier.bibliographicCitationLANGMUIR, v.24, no.7, pp.3417 - 3421-
dc.relation.isPartOfLANGMUIR-
dc.citation.titleLANGMUIR-
dc.citation.volume24-
dc.citation.number7-
dc.citation.startPage3417-
dc.citation.endPage3421-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalResearchAreaMaterials Science-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryChemistry, Physical-
dc.relation.journalWebOfScienceCategoryMaterials Science, Multidisciplinary-
dc.subject.keywordPlusCORE-SHELL PARTICLES-
dc.subject.keywordPlusNANOPARTICLES-
dc.subject.keywordPlusSPHERES-
dc.subject.keywordPlusFABRICATION-
dc.subject.keywordPlusRELEASE-
dc.subject.keywordPlusDOXORUBICIN-
dc.subject.keywordPlusCAPSULES-
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