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Effective methods to improve the biocompatibility of poly (dimethylsiloxane)

Authors
Park, Joong YullHwang, Chang MoLee, Sang-Hoon
Issue Date
20-3월-2008
Publisher
KOREAN BIOCHIP SOCIETY-KBCS
Keywords
biocompatibility; PDMS; microfluidic chip; fibroblast
Citation
BIOCHIP JOURNAL, v.2, no.1, pp.39 - 43
Indexed
SCIE
SCOPUS
Journal Title
BIOCHIP JOURNAL
Volume
2
Number
1
Start Page
39
End Page
43
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/123885
ISSN
1976-0280
Abstract
Poly (dimethylsiloxane) (Pi has become one of the popular materials in the field of bio-related microfluidic systems, and has been used for various biological assays. While the material is known to be biocompatible in general, it also has been reported that the attachment and survival rate of cells are limited on a Pi substrate. In this paper, a simple and relevant method to improve the biocompatibility of Pi is proposed; the effects of various treatments using ethanol, water, and boiling-water were evaluated. The results show that the boiling-water treatment is the most appropriate, time saving, and simple method to improve the biocompatibility of Pi
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