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Development and evaluation of a protein microarray chip for diagnosis of hepatitis C virus

Authors
Yuk, CSLee, HKKim, HTChoi, YKLee, BCChun, BHChung, N
Issue Date
10월-2004
Publisher
SPRINGER
Keywords
blood testing; hepatitis C virus; immuno-concentration; membrane; microarray; protein array
Citation
BIOTECHNOLOGY LETTERS, v.26, no.20, pp.1563 - 1568
Indexed
SCIE
SCOPUS
Journal Title
BIOTECHNOLOGY LETTERS
Volume
26
Number
20
Start Page
1563
End Page
1568
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/124325
DOI
10.1023/B:BILE.0000045653.92719.a4
ISSN
0141-5492
Abstract
A protein chip diagnostic kit was developed for the diagnosis of hepatitis C virus (HCV) based on the protein chip technique and the immuno-concentration method. This kit was designed for low-density protein chips and also for the availability of multiple sample screening. Applicability of the chip was evaluated using 96 blood specimens and the results were compared to results of an anti-HCV enzyme immunoassay (EIA) test. With further development, the technology associated with the development of this chip could be applied to the simultaneous detection of multiple protein-protein, protein-ligand interactions.
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