Serum adiponectin, C-reactive protein and TNF-alpha levels in obese Korean children
- Authors
- Shin, Jung Yeon; Kim, Soo Young; Jeung, Min Jee; Eun, So Hee; Woo, Chan Wook; Yoon, Soo-Young; Lee, Kee-Hyoung
- Issue Date
- 1월-2008
- Publisher
- WALTER DE GRUYTER GMBH
- Keywords
- inflammatory mediator; adiponectin; CRP; TNF-alpha; obesity; children
- Citation
- JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, v.21, no.1, pp.23 - 29
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
- Volume
- 21
- Number
- 1
- Start Page
- 23
- End Page
- 29
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/124512
- ISSN
- 0334-018X
- Abstract
- Aim: To determine whether there are differences of serum adiponectin, CRP and TNF-alpha levels between obese and non-obese children and to investigate the relationship between childhood obesity and inflammation. Methods: A total of 103 (73 obese, 30 non-obese) children were evaluated for height, weight, blood pressure and body mass index (BMI). We measured serum adiponectin, hs-CRP, and TNF-alpha levels and analyzed their correlation with BMI, serum glucose, lipid profile and insulin resistance. Results: Serum adiponectin levels were significantly decreased in the obese children compared to non-obese children, and had a negative correlation with BMI, fasting glucose and HOMA-IR. Serum hs-CRP and TNF-alpha levels were increased in obese children compared to non-obese children, and had a positive correlation with BMI. Conclusions: Serum adiponectin level was decreased and serum CRP and TNF-alpha levels were increased in obese children. Our findings suggest that childhood obesity is associated with inflammatory processes.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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