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치매관련 유전자 검사의 임상적 고찰Clinical Aspects of Genetic Testing for Dementia
- Other Titles
- Clinical Aspects of Genetic Testing for Dementia
- Issue Date
- 2008
- Publisher
- 대한노인병학회
- Keywords
- Familial Alzheimer' s disease; Causal genes; Susceptible gene; Issues
- Citation
- Annals of geriatric medicine and research, v.12, no.1, pp.5 - 10
- Journal Title
- Annals of geriatric medicine and research
- Volume
- 12
- Number
- 1
- Start Page
- 5
- End Page
- 10
- ISSN
- 2508-4798
- Abstract
- Dementia is the progressive or chronic dysfunction of cortical or subcortical functions that results in complex cognitive decline and Alzheimer's disease is the most common etiology of dementia. Currently, causal genetic mutations such as amyloid precursor protein, presenilin 1, presenilin 2 in familial Alzheimer's disease and many susceptible genes including polymorphysm of apolipoprotein E have been reported. Furthermore, genetic testings are available in person at risk for Alzheimer's disease. However, besides from results of genetic testing, there are many issues such as economics, ethics, psychological and legal. So clinician should be considered these complexities before ordering genetic test for patients with/without Alzheimer's disease.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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