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파래 추출물의 항응고 활성과 항암 활성에 관한 연구The Anticoagulant and Anticancer Activities of Enteromorpha intestinalis Extracts

Other Titles
The Anticoagulant and Anticancer Activities of Enteromorpha intestinalis Extracts
Authors
임은정임은정김지영이유현효진녕김영준조홍연
Issue Date
2008
Publisher
한국식품영양학회
Keywords
anticoagulant; anticancer; Enteromorpha intestinalis; MTT assay.; anticoagulant; anticancer; Enteromorpha intestinalis; MTT assay.
Citation
한국식품영양학회지, v.21, no.1, pp.7 - 14
Indexed
KCI
Journal Title
한국식품영양학회지
Volume
21
Number
1
Start Page
7
End Page
14
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/125073
ISSN
1225-4339
Abstract
The study was performed to investigate the biological activity of Enteromorpha intestinalis. In order to examine its blood anti-coagulant effects, Enteromorpha intestinalis was extracted with cold water, methanol, hot water, HCl and NaOH. In general, the alkali extract of Enteromorpha intestinalis was approximately 17 times stronger than the control. The anti-cancer effects of select extracts(methanol, hot water, 0.1 N NaOH, 1 N NaOH) were determined in human melanoma cells(B16/ F10), fibrosarcoma cells(HT1080) and breast cancer cells(MCF7) by MTT assay. With the treatment of 250 ㎍/㎖ of methanol extracts. HT1080, B16/F10 and MCF7 cell viabilities significantly decreased to 8.06%, 3.62% and 10.10%, respectively. Thus these results strongly support the possibie use of Enteromorpha intestinalis as a functional materials.
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