In vitro activity of kaempferol isolated from the Impatiens balsamina alone and in combination with erythromycin or clindamycin against Propionibacterium acnes
DC Field | Value | Language |
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dc.contributor.author | Lim, Young-Hee | - |
dc.contributor.author | Kim, In-Hwan | - |
dc.contributor.author | Seo, Jung-Ju | - |
dc.date.accessioned | 2021-09-09T17:05:47Z | - |
dc.date.available | 2021-09-09T17:05:47Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2007-10 | - |
dc.identifier.issn | 1225-8873 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/125703 | - |
dc.description.abstract | The in vitro antibacterial activity against antibiotic-resistant Propionibacterium acnes of kaempferol isolated from the Impatiens balsamina alone and in combination with erythromycin or clindamycin antibiotics was investigated. The antibiotic combination effect against antibiotic-resistant P. acnes was studied by checkerboard test. Kaempferol and quercetin demonstrated antibacterial activities against P. acnes. Minimum inhibitory concentrations (MICs) for both compounds were <= 32 mu g/ml and <= 64 mu g/ml for clindamycin-sensitive and -resistant P. acnes, respectively. The four combination formulations (kaempferol and either erythromycin or clindamycin; quercetin and either erythromycin or clindamycin) exhibited a synergic inhibition of P. acnes growth. The combination of kaempferol with quercetin showed an indifferent effect. The combination of clindamycin with kaempferol or quercetin showed a greater synergic effect than that of erythromycin with kaempferol or quercetin. Thus, these combinations demonstrated the potential to treat acne. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MICROBIOLOGICAL SOCIETY KOREA | - |
dc.subject | CHRONIC INFLAMMATORY ACNE | - |
dc.subject | FLAVONOIDS | - |
dc.subject | SURVEILLANCE | - |
dc.subject | ANTIBIOTICS | - |
dc.subject | PSEUDOMONAS | - |
dc.subject | RESISTANCE | - |
dc.subject | THERAPY | - |
dc.title | In vitro activity of kaempferol isolated from the Impatiens balsamina alone and in combination with erythromycin or clindamycin against Propionibacterium acnes | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lim, Young-Hee | - |
dc.contributor.affiliatedAuthor | Kim, In-Hwan | - |
dc.identifier.scopusid | 2-s2.0-35648995463 | - |
dc.identifier.wosid | 000250576400015 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROBIOLOGY, v.45, no.5, pp.473 - 477 | - |
dc.relation.isPartOf | JOURNAL OF MICROBIOLOGY | - |
dc.citation.title | JOURNAL OF MICROBIOLOGY | - |
dc.citation.volume | 45 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 473 | - |
dc.citation.endPage | 477 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART001188790 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.subject.keywordPlus | CHRONIC INFLAMMATORY ACNE | - |
dc.subject.keywordPlus | FLAVONOIDS | - |
dc.subject.keywordPlus | SURVEILLANCE | - |
dc.subject.keywordPlus | ANTIBIOTICS | - |
dc.subject.keywordPlus | PSEUDOMONAS | - |
dc.subject.keywordPlus | RESISTANCE | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordAuthor | Propionibacterium acnes | - |
dc.subject.keywordAuthor | kaempferol | - |
dc.subject.keywordAuthor | erythromycin | - |
dc.subject.keywordAuthor | clindamycin | - |
dc.subject.keywordAuthor | checkerboard test | - |
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