Relationship between blood pressure parameters and pulse wave velocity in normotensive and hypertensive subjects: invasive study
DC Field | Value | Language |
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dc.contributor.author | Kim, E. J. | - |
dc.contributor.author | Park, C. G. | - |
dc.contributor.author | Park, J. S. | - |
dc.contributor.author | Suh, S. Y. | - |
dc.contributor.author | Choi, C. U. | - |
dc.contributor.author | Kim, J. W. | - |
dc.contributor.author | Kim, S. H. | - |
dc.contributor.author | Lim, H. E. | - |
dc.contributor.author | Rha, S. W. | - |
dc.contributor.author | Seo, H. S. | - |
dc.contributor.author | Oh, D. J. | - |
dc.date.accessioned | 2021-09-09T17:28:43Z | - |
dc.date.available | 2021-09-09T17:28:43Z | - |
dc.date.created | 2021-06-10 | - |
dc.date.issued | 2007-02 | - |
dc.identifier.issn | 0950-9240 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/125822 | - |
dc.description.abstract | Blood pressure ( BP) is one of the most important contributing factors to pulse wave velocity (PWV), a classic measure of arterial stiffness. Although there have been many non-invasive studies to show the relation between arterial stiffness and BP, the results are controversial. The aim of this study is to evaluate the role of BP as an influencing factor on PWV using invasive method. We observed 174 normotensive and untreated hypertensive subjects using coronary angiography. Arterial stiffness was assessed through aorto-femoral PWV by foot-to-foot velocity method using fluid-filled system. And BP was measured by pressure wave at the right common femoral artery. From univariate analysis, age, diabetes mellitus (DM), hypertension, waist, waist-to-hip ratio, total cholesterol-to-high-density lipoprotein cholesterol ratio, systolic BP (SBP), pulse pressure ( PP) and mean arterial pressure ( MAP) showed significant association with PWV. To avoid multiple colinearity among SBP, PP and MAP, we performed multiple regression analysis predicting PWV thrice. Age, DM and each BP were significantly and consistently correlated to PWV. In the first and third modules, compared to age, SBP and MAP were less strong predictors, respectively. However, PP was the stronger predictor than age and DM in the second module. Lastly, we simultaneously forced MAP and PP with other variables in the fourth multivariate analysis. Age, DM and PP remained significantly correlated with PWV, but the significance of MAP was lost. This is the first invasive study to suggest that PP has the strongest correlation with PWV among a variety of BP parameters. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.subject | CARDIOVASCULAR RISK-FACTORS | - |
dc.subject | CORONARY-ARTERY-DISEASE | - |
dc.subject | STAGE RENAL-DISEASE | - |
dc.subject | AORTIC STIFFNESS | - |
dc.subject | INDEPENDENT PREDICTOR | - |
dc.subject | HEART-DISEASE | - |
dc.subject | MORTALITY | - |
dc.subject | INDEX | - |
dc.subject | ATHEROSCLEROSIS | - |
dc.subject | SMOKING | - |
dc.title | Relationship between blood pressure parameters and pulse wave velocity in normotensive and hypertensive subjects: invasive study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, S. H. | - |
dc.identifier.doi | 10.1038/sj.jhh.1002120 | - |
dc.identifier.scopusid | 2-s2.0-33847040379 | - |
dc.identifier.wosid | 000243565500007 | - |
dc.identifier.bibliographicCitation | JOURNAL OF HUMAN HYPERTENSION, v.21, no.2, pp.141 - 148 | - |
dc.relation.isPartOf | JOURNAL OF HUMAN HYPERTENSION | - |
dc.citation.title | JOURNAL OF HUMAN HYPERTENSION | - |
dc.citation.volume | 21 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 141 | - |
dc.citation.endPage | 148 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.subject.keywordPlus | CARDIOVASCULAR RISK-FACTORS | - |
dc.subject.keywordPlus | CORONARY-ARTERY-DISEASE | - |
dc.subject.keywordPlus | STAGE RENAL-DISEASE | - |
dc.subject.keywordPlus | AORTIC STIFFNESS | - |
dc.subject.keywordPlus | INDEPENDENT PREDICTOR | - |
dc.subject.keywordPlus | HEART-DISEASE | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | INDEX | - |
dc.subject.keywordPlus | ATHEROSCLEROSIS | - |
dc.subject.keywordPlus | SMOKING | - |
dc.subject.keywordAuthor | pulse wave velocity | - |
dc.subject.keywordAuthor | pulse pressure | - |
dc.subject.keywordAuthor | large artery stiffness | - |
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