Role of arterial stiffness in the association between hand grip strength and cardiovascular events: the Korean Genome and Epidemiology Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Woohyeun | - |
dc.contributor.author | Kim, Seong Hwan | - |
dc.contributor.author | Choi, Cheol Ung | - |
dc.contributor.author | Lee, Seung Ku | - |
dc.contributor.author | Kang, Dong Oh | - |
dc.contributor.author | Choi, Jah Yeon | - |
dc.contributor.author | Roh, Seung-Young | - |
dc.contributor.author | Na, Jin Oh | - |
dc.contributor.author | Kim, Jin Won | - |
dc.contributor.author | Kim, Eung Ju | - |
dc.contributor.author | Rha, Seung-Woon | - |
dc.contributor.author | Park, Chang Gyu | - |
dc.contributor.author | Seo, Hong Seog | - |
dc.contributor.author | Shin, Chol | - |
dc.date.accessioned | 2021-11-19T10:40:32Z | - |
dc.date.available | 2021-11-19T10:40:32Z | - |
dc.date.created | 2021-08-30 | - |
dc.date.issued | 2021-06 | - |
dc.identifier.issn | 0263-6352 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/127984 | - |
dc.description.abstract | Background: Hand grip strength (HGS) has been associated with cardiovascular events. However, the exact mechanism responsible for the inverse association between HGS and cardiovascular events has not been established. The aim of this study was to assess whether arterial stiffness mediates this association. Methods: We studied 1508 participants (age; 60 +/- 5, men; 47.5%) from the Ansan cohort of the Korean Genome Epidemiology Study. Participants were assessed for various parameters of arterial stiffness as well as HGS. The augmentation index (AIx) and brachial-ankle pulse wave velocity (baPWV) were evaluated by using an applanation tonometer and automated waveform analyzer, respectively. Carotid intima medial thickness (IMT) was measured by B-mode ultrasonogram with a 7.5-MHz linear array transducer. HGS was evaluated using a Jamar dynamometer. Results: With increased grip strength, AIx decreased (r = 0.437, P < 0.001). baPWV (r = 0.044, P = 0.107) and carotid IMT (r = 0.005, P = 0.856) had no significant correlation with grip strength. This trend was consistently observed regardless of hypertension, but was more pronounced in participants with hypertension. Conclusion: HGS was significantly correlated with AIx, but not with baPWV and carotid IMT. Our findings suggest that central arterial stiffness could mediate the association between HGS and cardiovascular events. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.title | Role of arterial stiffness in the association between hand grip strength and cardiovascular events: the Korean Genome and Epidemiology Study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Seong Hwan | - |
dc.contributor.affiliatedAuthor | Choi, Cheol Ung | - |
dc.contributor.affiliatedAuthor | Rha, Seung-Woon | - |
dc.contributor.affiliatedAuthor | Shin, Chol | - |
dc.identifier.doi | 10.1097/HJH.0000000000002753 | - |
dc.identifier.scopusid | 2-s2.0-85106538378 | - |
dc.identifier.wosid | 000647705300021 | - |
dc.identifier.bibliographicCitation | JOURNAL OF HYPERTENSION, v.39, no.6, pp.1203 - 1209 | - |
dc.relation.isPartOf | JOURNAL OF HYPERTENSION | - |
dc.citation.title | JOURNAL OF HYPERTENSION | - |
dc.citation.volume | 39 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1203 | - |
dc.citation.endPage | 1209 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.subject.keywordPlus | ALL-CAUSE MORTALITY | - |
dc.subject.keywordPlus | PHYSICAL-FITNESS | - |
dc.subject.keywordPlus | BLOOD-PRESSURE | - |
dc.subject.keywordPlus | HEALTHY-MEN | - |
dc.subject.keywordPlus | PREDICTOR | - |
dc.subject.keywordPlus | AGE | - |
dc.subject.keywordPlus | CORONARY | - |
dc.subject.keywordPlus | WOMEN | - |
dc.subject.keywordAuthor | arterial stiffness | - |
dc.subject.keywordAuthor | cardiovascular events | - |
dc.subject.keywordAuthor | hand grip strength | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.