Different Influence of Blood Pressure on New-Onset Atrial Fibrillation in Pre- and Postmenopausal Women A Nationwide Population-Based Study
DC Field | Value | Language |
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dc.contributor.author | Kim, Yun Gi | - |
dc.contributor.author | Han, Kyung-Do | - |
dc.contributor.author | Kim, Do Young | - |
dc.contributor.author | Choi, Yun Young | - |
dc.contributor.author | Choi, Ha Young | - |
dc.contributor.author | Roh, Seung-Young | - |
dc.contributor.author | Shim, Jaemin | - |
dc.contributor.author | Kim, Jin Seok | - |
dc.contributor.author | Choi, Jong-Il | - |
dc.contributor.author | Kim, Young-Hoon | - |
dc.date.accessioned | 2021-11-20T07:40:56Z | - |
dc.date.available | 2021-11-20T07:40:56Z | - |
dc.date.created | 2021-08-30 | - |
dc.date.issued | 2021-05 | - |
dc.identifier.issn | 0194-911X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/128091 | - |
dc.description.abstract | The characteristics of hypertension in pre- and postmenopausal women are different. Hypertension is a known risk factor for new-onset atrial fibrillation (AF), but its interaction with the menopause state is not fully established. We investigated whether menopause influences the adverse impact of high blood pressure on new-onset AF using a nationwide population-based cohort in Korea. People who underwent both a national health check-up and national cancer screening program were included in this study. A total of 3 280 834 women were assessed with 23 781 070 person*year follow-up data. Menopause was observed in 1 439 161 women. The risk of new-onset AF and blood pressure showed a linear relationship in premenopausal women (P<0.001 for both systolic and diastolic blood pressure). The risk of new-onset AF was increased by 58.8% if systolic blood pressure was >= 160 mm Hg compared with the reference group (100 mm Hg <= systolic blood pressure <110 mm Hg; hazard ratio=1.588 [95% CI, 1.383-1.823]) in premenopause group. However, no consistent correlation was observed between blood pressure and the risk of new-onset AF in postmenopausal women. The increased risk of new-onset AF attributable to elevated blood pressure was more pronounced in patients not taking antihypertension medications (P for interaction <0.001). In conclusion, elevated blood pressure, especially systolic blood pressure, was a significant risk factor for new-onset AF in premenopausal women. Postmenopausal women showed a significantly attenuated association between blood pressure and the risk of new-onset AF. Elevated systolic blood pressure had a more profound impact on new-onset AF in women not taking medications for hypertension. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.title | Different Influence of Blood Pressure on New-Onset Atrial Fibrillation in Pre- and Postmenopausal Women A Nationwide Population-Based Study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shim, Jaemin | - |
dc.contributor.affiliatedAuthor | Choi, Jong-Il | - |
dc.identifier.doi | 10.1161/HYPERTENSIONAHA.120.16513 | - |
dc.identifier.scopusid | 2-s2.0-85104046906 | - |
dc.identifier.wosid | 000639317000009 | - |
dc.identifier.bibliographicCitation | HYPERTENSION, v.77, no.5, pp.1500 - 1509 | - |
dc.relation.isPartOf | HYPERTENSION | - |
dc.citation.title | HYPERTENSION | - |
dc.citation.volume | 77 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1500 | - |
dc.citation.endPage | 1509 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | RHYTHM MANAGEMENT | - |
dc.subject.keywordPlus | EARLY MENOPAUSE | - |
dc.subject.keywordPlus | HYPERTENSION | - |
dc.subject.keywordPlus | AGE | - |
dc.subject.keywordAuthor | atrial fibrillation | - |
dc.subject.keywordAuthor | blood pressure | - |
dc.subject.keywordAuthor | hypertension | - |
dc.subject.keywordAuthor | menopause | - |
dc.subject.keywordAuthor | risk factors | - |
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