Long-Term Outcomes of Patients With Late Presentation of ST-Segment Elevation Myocardial Infarction
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Kyung Hoon | - |
dc.contributor.author | Han, Xiongyi | - |
dc.contributor.author | Ahn, Joon Ho | - |
dc.contributor.author | Hyun, Dae Young | - |
dc.contributor.author | Kim, Min Chul | - |
dc.contributor.author | Sim, Doo Sun | - |
dc.contributor.author | Hong, Young Joon | - |
dc.contributor.author | Kim, Ju Han | - |
dc.contributor.author | Ahn, Youngkeun | - |
dc.contributor.author | Hwang, Jin Yong | - |
dc.contributor.author | Oh, Seok Kyu | - |
dc.contributor.author | Cha, Kwang Soo | - |
dc.contributor.author | Choi, Cheol Ung | - |
dc.contributor.author | Hwang, Kyung-Kuk | - |
dc.contributor.author | Gwon, Hyeon Cheol | - |
dc.contributor.author | Jeong, Myung Ho | - |
dc.date.accessioned | 2021-11-21T09:41:09Z | - |
dc.date.available | 2021-11-21T09:41:09Z | - |
dc.date.created | 2021-08-30 | - |
dc.date.issued | 2021-04-20 | - |
dc.identifier.issn | 0735-1097 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/128221 | - |
dc.description.abstract | BACKGROUND Real-world data on baseline characteristics, clinical practice, and outcomes of late presentation (12 to 48 h of symptom onset) in patients with ST-segment elevation myocardial infarction (STEMI) are limited. OBJECTIVES This study aimed to investigate real-world features of STEMI late presenters in the contemporary percutaneous coronary intervention (PCI) era. METHODS Of 13,707 patients from the Korea Acute Myocardial Infarction Registry-National Institutes of Health database, 5,826 consecutive patients diagnosed with STEMI within 48 h of symptom onset during 2011 to 2015 were categorized as late (12 to 48 h; n = 624) or early (< 12 h; n = 5,202) presenters. Coprimary outcomes were 180-day and 3-year all-cause mortality. RESULTS Late presenters had remarkably worse clinical outcomes than early presenters (180-day mortality: 10.7% vs. 6.8%; 3-year mortality: 16.2% vs. 10.6%; both log-rank p < 0.001), whereas presentation at $12 h of symptom onset was not independently associated with increased mortality after STEMI. The use of invasive interventional procedures abruptly decreased from the first (< 12 h) to the second (12 to 24 h) 12-h interval of symptom-to-door time ("no primary PCI strategy" increased from 4.9% to 12.4%, and 'no PCI" from 2.3% to 6.6%; both p < 0.001). Mortality rates abruptly increased from the first to the second 12-h interval of symptom-to-door time (from 6.8% to 11.2% for 180-day mortality; from 10.6% to 17.3% for 3-year mortality; all p < 0.05). CONCLUSIONS Data from a nationwide prospective Korean registry reveal that inverse steep differences in the use of invasive interventional procedures and mortality rates were found between early and late presenters after STEMI. A multidisciplinary approach is required in identifying late presenters of STEMI who can benefit from invasive interventional procedures until further studied. (J Am Coll Cardiol 2021;77:1859-70) (c) 2021 by the American College of Cardiology Foundation. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | MECHANICAL REPERFUSION | - |
dc.subject | SYMPTOM-ONSET | - |
dc.subject | TASK-FORCE | - |
dc.subject | MANAGEMENT | - |
dc.subject | SALVAGE | - |
dc.subject | TIME | - |
dc.subject | ANGIOPLASTY | - |
dc.subject | MORTALITY | - |
dc.subject | TRIALS | - |
dc.title | Long-Term Outcomes of Patients With Late Presentation of ST-Segment Elevation Myocardial Infarction | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Cheol Ung | - |
dc.identifier.doi | 10.1016/j.jacc.2021.02.041 | - |
dc.identifier.scopusid | 2-s2.0-85103702371 | - |
dc.identifier.wosid | 000640242300003 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, v.77, no.15, pp.1859 - 1870 | - |
dc.relation.isPartOf | JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | - |
dc.citation.title | JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | - |
dc.citation.volume | 77 | - |
dc.citation.number | 15 | - |
dc.citation.startPage | 1859 | - |
dc.citation.endPage | 1870 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | MECHANICAL REPERFUSION | - |
dc.subject.keywordPlus | SYMPTOM-ONSET | - |
dc.subject.keywordPlus | TASK-FORCE | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | SALVAGE | - |
dc.subject.keywordPlus | TIME | - |
dc.subject.keywordPlus | ANGIOPLASTY | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | TRIALS | - |
dc.subject.keywordAuthor | percutaneous coronary | - |
dc.subject.keywordAuthor | intervention | - |
dc.subject.keywordAuthor | registries | - |
dc.subject.keywordAuthor | Republic of Korea | - |
dc.subject.keywordAuthor | ST-segment elevation myocardial infarction | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.