Generation of a WA14 hESC sub-line carrying a hemizygous ABCD1 (C.1696_1710 del) mutation introduced by CRISPR/Cas9 technology
DC Field | Value | Language |
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dc.contributor.author | Hong, W. | - |
dc.contributor.author | Yun, W. | - |
dc.contributor.author | Choi, W. | - |
dc.contributor.author | Son, D. | - |
dc.contributor.author | Song, G. | - |
dc.contributor.author | You, S. | - |
dc.date.accessioned | 2021-12-03T00:41:21Z | - |
dc.date.available | 2021-12-03T00:41:21Z | - |
dc.date.created | 2021-08-31 | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 1873-5061 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/128999 | - |
dc.description.abstract | ATP-binding cassette transporter subfamily D member 1 (ABCD1) gene is a member of ABC transporter super family, which conduct peroxisomal import of very long chain fatty acid and crucial underlying factor that induces X-linked adrenoleukodystrophy (X-ALD) when the gene is defected. Here, we report the generation of a human embryonic stem cell sub-line harboring a hemizygous ABCD1 mutation (C.1696_1710 del) using CRISPR/Cas9 system. Established line expresses pluripotency marker genes, can be differentiated to three germ layers, and maintains a normal karyotype. © 2021 The Authors | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | Elsevier B.V. | - |
dc.title | Generation of a WA14 hESC sub-line carrying a hemizygous ABCD1 (C.1696_1710 del) mutation introduced by CRISPR/Cas9 technology | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Song, G. | - |
dc.contributor.affiliatedAuthor | You, S. | - |
dc.identifier.doi | 10.1016/j.scr.2021.102244 | - |
dc.identifier.scopusid | 2-s2.0-85101061389 | - |
dc.identifier.wosid | 000631896900035 | - |
dc.identifier.bibliographicCitation | Stem Cell Research, v.52 | - |
dc.relation.isPartOf | Stem Cell Research | - |
dc.citation.title | Stem Cell Research | - |
dc.citation.volume | 52 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Cell & Tissue Engineering | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
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