Performance Evaluation of Alere i Influenza A&B in Detecting Influenza Viruses A and B
DC Field | Value | Language |
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dc.contributor.author | Kim, Ha Nui | - |
dc.contributor.author | Jang, Woong Sik | - |
dc.contributor.author | Nam, Jeonghun | - |
dc.contributor.author | Mihn, Do-Cic | - |
dc.contributor.author | Lim, Chae Seung | - |
dc.date.accessioned | 2021-12-04T21:00:45Z | - |
dc.date.available | 2021-12-04T21:00:45Z | - |
dc.date.created | 2021-08-30 | - |
dc.date.issued | 2021-01 | - |
dc.identifier.issn | 0091-7370 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/129448 | - |
dc.description.abstract | Objective. Alere i Influenza A&B is an isothermal nucleic acid amplification-based integrated system used for detecting and differentiating between influenza virus A and influenza virus 13. We evaluated the clinical performances of Alere i Influenza A&B compared to that of real-time PCR, multiplex real-time PCR, and two rapid influenza diagnostic kits. Methods. Nasopharyngeal aspiration specimens (n=315) from patients with signs of acute respiratory infection were collected between 2015 and 2016. Samples were tested using real-time PCR, the multiplex RT-PCR Anyplex II RV16 Detection kit, Akre i Influenza A&B, BD Veritor (TM) System Flu A+B, and the Sofia Influenza A+B Fluorescence Immunoassay. Positive influenza specimens detected by the Anyplex II RV16 Detection kit were tested by real-time PCR. Results. Compared to that of multiplex RT-PCR (influenza A, n=88; influenza B, n=82; influenza-negative, n=145), the sensitivities of Alere i, Sofia, and Veritor for influenza A were 97.7%, 72.7%, and 71.6%, respectively, whereas for influenza B, the sensitivities were 96.3%, 80.4%, and 75.6%, respectively. The specificity of Alere i, Sofia, and Veritor was 100.0%. Conclusions. The clinical performance of Alere i Influenza A&B is satisfactory, with the advantage of a significantly shorter test time than other molecular assays. It is suitable for point-of-care testing and rapid influenza diagnostic tests because of its high sensitivity and specificity. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ASSOC CLINICAL SCIENTISTS | - |
dc.subject | DIAGNOSIS | - |
dc.subject | ACCURACY | - |
dc.subject | MANAGEMENT | - |
dc.subject | FLU | - |
dc.title | Performance Evaluation of Alere i Influenza A&B in Detecting Influenza Viruses A and B | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lim, Chae Seung | - |
dc.identifier.scopusid | 2-s2.0-85102332478 | - |
dc.identifier.wosid | 000625297000014 | - |
dc.identifier.bibliographicCitation | ANNALS OF CLINICAL AND LABORATORY SCIENCE, v.51, no.1, pp.106 - 111 | - |
dc.relation.isPartOf | ANNALS OF CLINICAL AND LABORATORY SCIENCE | - |
dc.citation.title | ANNALS OF CLINICAL AND LABORATORY SCIENCE | - |
dc.citation.volume | 51 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 106 | - |
dc.citation.endPage | 111 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Medical Laboratory Technology | - |
dc.relation.journalWebOfScienceCategory | Medical Laboratory Technology | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | ACCURACY | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | FLU | - |
dc.subject.keywordAuthor | influenza | - |
dc.subject.keywordAuthor | Alere i Influenza A& | - |
dc.subject.keywordAuthor | B | - |
dc.subject.keywordAuthor | RIDT | - |
dc.subject.keywordAuthor | Real-time PCR | - |
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