Impact of stent designs ofsecond-generation drug-elutingstents on long-term outcomes in coronary bifurcation lesions
DC Field | Value | Language |
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dc.contributor.author | Jang, Woo Jin | - |
dc.contributor.author | Chun, Woo Jung | - |
dc.contributor.author | Park, Ik Hyun | - |
dc.contributor.author | Choi, Ki Hong | - |
dc.contributor.author | Song, Young Bin | - |
dc.contributor.author | Koo, Bon-Kwon | - |
dc.contributor.author | Doh, Joon-Hyung | - |
dc.contributor.author | Hong, Soon-Jun | - |
dc.contributor.author | Nam, Chang-Wook | - |
dc.contributor.author | Gwon, Hyeon-Cheol | - |
dc.date.accessioned | 2021-12-07T16:42:34Z | - |
dc.date.available | 2021-12-07T16:42:34Z | - |
dc.date.created | 2021-08-30 | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 1522-1946 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/130129 | - |
dc.description.abstract | Objectives We compared the long-term clinical outcomes of four different types of second-generation drug-eluting stents (DESs) in coronary bifurcation lesions. Background Clinical outcomes of different designs of second-generation DESs are not well known in bifurcation lesions. Methods Patients who underwent percutaneous coronary intervention with second-generation DESs for coronary bifurcation lesion were enrolled from 21 centers in South Korea. A total of 2,526 patients was evaluated and divided into four treatment groups according to DES type: bioabsorbable polymer biolimus-eluting stent (BP-BES group,n= 514), platinum chromium everolimus-eluting stent (PtCr-EES group,n= 473), cobalt nickel zotarolimus-eluting stent (CoNi-ZES group,n= 736), or cobalt chromium everolimus-eluting stent (CoCr-EES group,n= 803). Primary outcome was target lesion failure (TLF, defined as a composite of cardiac death, target vessel myocardial infarction, or target lesion revascularization). Inverse probability of treatment weighting (IPTW) was performed to reduce selection bias and potential confounding factors. Results For 5 years of follow-up, the rates of TLF among the four DES groups were not significantly different (6.2% for BP-BES group, 8.2% for PtCr-EES group, 6.5% for CoNi-ZES group, and 8.6% for CoCr-EES group,p= .434). The results were consistent after IPTW adjustment (6.8, 8.4, 6.0, and 7.5%, respectively,p= .554). In subgroup analysis, the similarity of long-term outcomes among the four different types of second-generation DES was consistent across subgroups regardless of side branch treatment (pfor interaction = .691). Conclusion There seems to be no significant difference in long-term clinical outcomes among patients who received different types of second-generation DES for coronary bifurcation lesion. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.subject | DUAL ANTIPLATELET THERAPY | - |
dc.subject | FOCUSED UPDATE | - |
dc.subject | ZOTAROLIMUS | - |
dc.subject | SAFETY | - |
dc.title | Impact of stent designs ofsecond-generation drug-elutingstents on long-term outcomes in coronary bifurcation lesions | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Hong, Soon-Jun | - |
dc.identifier.doi | 10.1002/ccd.29137 | - |
dc.identifier.scopusid | 2-s2.0-85088805892 | - |
dc.identifier.wosid | 000553592300001 | - |
dc.identifier.bibliographicCitation | CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, v.98, no.3, pp.458 - 467 | - |
dc.relation.isPartOf | CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS | - |
dc.citation.title | CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS | - |
dc.citation.volume | 98 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 458 | - |
dc.citation.endPage | 467 | - |
dc.type.rims | ART | - |
dc.type.docType | Article; Early Access | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | DUAL ANTIPLATELET THERAPY | - |
dc.subject.keywordPlus | FOCUSED UPDATE | - |
dc.subject.keywordPlus | ZOTAROLIMUS | - |
dc.subject.keywordPlus | SAFETY | - |
dc.subject.keywordAuthor | coronary bifurcation lesion | - |
dc.subject.keywordAuthor | percutaneous coronary intervention | - |
dc.subject.keywordAuthor | second-generation drug-eluting stent | - |
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