Early Post-Rewarming Fever Is Associated with Favorable 6-Month Neurologic Outcomes in Patients with Out-Of-Hospital Cardiac Arrest: A Multicenter Registry Study
DC Field | Value | Language |
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dc.contributor.author | Lee, Hyoung Youn | - |
dc.contributor.author | Lee, Dong Hun | - |
dc.contributor.author | Lee, Byung Kook | - |
dc.contributor.author | Jeung, Kyung Woon | - |
dc.contributor.author | Jung, Yong Hun | - |
dc.contributor.author | Choi, Seung Phil | - |
dc.contributor.author | Park, Jung Soo | - |
dc.contributor.author | Lee, Jae Hoon | - |
dc.contributor.author | Han, Kap Su | - |
dc.contributor.author | Min, Yong Il | - |
dc.date.accessioned | 2021-12-09T03:41:30Z | - |
dc.date.available | 2021-12-09T03:41:30Z | - |
dc.date.created | 2021-08-30 | - |
dc.date.issued | 2020-09 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/130476 | - |
dc.description.abstract | We investigated the association between post-rewarming fever (PRF) and 6-month neurologic outcomes in cardiac arrest survivors. This was a multicenter study based on a registry of comatose adult (>= 18 years) out-of-hospital cardiac arrest (OHCA) survivors who underwent targeted temperature management between October 2015 to December 2018. PRF was defined as peak temperature >= 38.0 degrees C within 72 h after completion of rewarming, and PRF timing was categorized as within 24, 24-48, and 48-72 h epochs. The primary outcome was neurologic outcomes at six months after cardiac arrest. Unfavorable neurologic outcome was defined as cerebral performance categories three to five. A total of 1031 patients were included, and 642 (62.3%) had unfavorable neurologic outcomes. PRF developed in 389 (37.7%) patients in 72 h after rewarming: within 24 h in 150 (38.6%), in 24-48 h in 155 (39.8%), and in 48-72 h in 84 (21.6%). PRF was associated with improved neurologic outcomes (odds ratio (OR), 0.633; 95% confidence interval (CI), 0.416-0.963). PRF within 24 h (OR, 0.355; 95% CI, 0.191-0.659), but not in 24-48 h or 48-72 h, was associated with unfavorable neurologic outcomes. Early PRF within 24 h after rewarming was associated with favorable neurologic outcomes. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.subject | THERAPEUTIC HYPOTHERMIA | - |
dc.subject | TEMPERATURE MANAGEMENT | - |
dc.subject | HYPERTHERMIA | - |
dc.subject | RESUSCITATION | - |
dc.subject | HYPOPERFUSION | - |
dc.subject | SURVIVORS | - |
dc.subject | SEPSIS | - |
dc.subject | UPDATE | - |
dc.subject | BRAIN | - |
dc.subject | TIME | - |
dc.title | Early Post-Rewarming Fever Is Associated with Favorable 6-Month Neurologic Outcomes in Patients with Out-Of-Hospital Cardiac Arrest: A Multicenter Registry Study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Han, Kap Su | - |
dc.identifier.doi | 10.3390/jcm9092927 | - |
dc.identifier.wosid | 000580269200001 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MEDICINE, v.9, no.9 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.title | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.volume | 9 | - |
dc.citation.number | 9 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | THERAPEUTIC HYPOTHERMIA | - |
dc.subject.keywordPlus | TEMPERATURE MANAGEMENT | - |
dc.subject.keywordPlus | HYPERTHERMIA | - |
dc.subject.keywordPlus | RESUSCITATION | - |
dc.subject.keywordPlus | HYPOPERFUSION | - |
dc.subject.keywordPlus | SURVIVORS | - |
dc.subject.keywordPlus | SEPSIS | - |
dc.subject.keywordPlus | UPDATE | - |
dc.subject.keywordPlus | BRAIN | - |
dc.subject.keywordPlus | TIME | - |
dc.subject.keywordAuthor | out-of-hospital cardiac arrest | - |
dc.subject.keywordAuthor | targeted temperature management | - |
dc.subject.keywordAuthor | prognosis | - |
dc.subject.keywordAuthor | fever | - |
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