Vesicoureteral Reflux and Renal Scarring in Children with Acute Pyelonephritis: the Role of Late 6-month Dimercaptosuccinic Acid Renal Scan
DC Field | Value | Language |
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dc.contributor.author | Kyeong Eun Oh | - |
dc.contributor.author | 임형은 | - |
dc.contributor.author | Kee Hwan Yoo | - |
dc.date.accessioned | 2021-12-10T11:42:02Z | - |
dc.date.available | 2021-12-10T11:42:02Z | - |
dc.date.created | 2021-08-31 | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 2384-0242 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/130798 | - |
dc.description.abstract | Purpose: The aim of this study is to evaluate the clinical utility of late 6-month dimercapto-succinic acid (DMSA) renal scan in predicting vesicoureteral reflux (VUR) and long-lasting renal scars in children with first acute pyelonephritis (APN). Methods: A retrospective case study of children admitted with APN from January 2010 to July 2017 was performed. The study included patients with voiding cystourethrography (VCUG) and acute and late 6-month DMSA scan. We analyzed the clinical, laboratory and imaging findings of patients with and without late cortical defects at 6 months and those with or without VUR. Results: Among 145 children with APN, 50 (34.5%) had cortical defects on the late DMSA renal scan and 60 (41.4%) showed VUR. Thirteen of 38 (34.2%) children undergoing 18-month DMSA renal scan showed a long-lasting renal scars. Compared with children without late cortical defects, patients with late 6-month cortical defects had a higher incidence of VUR and long-lasting renal scars, and relapse of UTI (all P <0.05). In a multivariable analysis, both high-grade VUR and relapse of UTI were independently correlated with the presence of late 6-month cortical defects (P <0.05). Late cortical defects and relapse of UTI were also associated with the presence of VUR (P<0.05). Only the late 6-mo cortical defects was an independent predictor of long-lasting renal scars in children with APN (P <0.05). Conclusion: An abnormal late 6-month DMSA renal scan may be useful in identifying VUR and long-lasting renal scars in children diagnosed with APN. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | 대한소아신장학회 | - |
dc.title | Vesicoureteral Reflux and Renal Scarring in Children with Acute Pyelonephritis: the Role of Late 6-month Dimercaptosuccinic Acid Renal Scan | - |
dc.title.alternative | Vesicoureteral Reflux and Renal Scarring in Children with Acute Pyelonephritis: the Role of Late 6-month Dimercaptosuccinic Acid Renal Scan | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 임형은 | - |
dc.identifier.bibliographicCitation | Childhood Kidney Diseases, v.24, no.2, pp.98 - 106 | - |
dc.relation.isPartOf | Childhood Kidney Diseases | - |
dc.citation.title | Childhood Kidney Diseases | - |
dc.citation.volume | 24 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 98 | - |
dc.citation.endPage | 106 | - |
dc.type.rims | ART | - |
dc.identifier.kciid | ART002639037 | - |
dc.description.journalClass | 2 | - |
dc.description.journalRegisteredClass | kci | - |
dc.description.journalRegisteredClass | other | - |
dc.subject.keywordAuthor | Renal scarring | - |
dc.subject.keywordAuthor | Acute pyelonephritis | - |
dc.subject.keywordAuthor | Vesicoureteral reflux | - |
dc.subject.keywordAuthor | Dimercaptosuccinic acid renal scan | - |
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