Functional Test Scales for Evaluating Cell-Based Therapies in Animal Models of Spinal Cord Injury
- Authors
- Kim, Woon Ryoung; Kang, Minjin; Park, Heejoo; Ham, Hyun-Joo; Lee, Hyunji; Geum, Dongho
- Issue Date
- 2017
- Publisher
- HINDAWI LTD
- Citation
- STEM CELLS INTERNATIONAL, v.2017
- Indexed
- SCIE
SCOPUS
- Journal Title
- STEM CELLS INTERNATIONAL
- Volume
- 2017
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/132428
- DOI
- 10.1155/2017/5160261
- ISSN
- 1687-966X
- Abstract
- Recently, spinal cord researchers have focused on multifaceted approaches for the treatment of spinal cord injury (SCI). However, as there is no cure for the deficits produced by SCI, various therapeutic strategies have been examined using animal models. Due to the lack of standardized functional assessment tools for use in such models, it is important to choose a suitable animal model and precise behavioral test when evaluating the efficacy of potential SCI treatments. In the present review, we discuss recent evidence regarding functional recovery in various animal models of SCI, summarize the representative models currently used, evaluate recent cell-based therapeutic approaches, and aim to identify the most precise and appropriate scales for functional assessment in such research.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.