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The Epidemiology and Economic Burden of Clostridium difficile Infection in Korea

Authors
Choi, Hyung-YunPark, So-YounKim, Young-AeYoon, Tai-YoungChoi, Joong-MyungChoe, Bong-KeunAhn, So-HeeYoon, Seok-JunLee, Ye-RinOh, In-Hwan
Issue Date
2015
Publisher
HINDAWI LTD
Citation
BIOMED RESEARCH INTERNATIONAL, v.2015
Indexed
SCIE
SCOPUS
Journal Title
BIOMED RESEARCH INTERNATIONAL
Volume
2015
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/133169
DOI
10.1155/2015/510386
ISSN
2314-6133
Abstract
The prevalence of Clostridium difficile infection and the associated burden have recently increased in many countries. While the main risk factors for C. difficile infection include old age and antibiotic use, the prevalence of this infection is increasing in low- risk groups. These trends highlight the need for research on C. difficile infection. This study pointed out the prevalence and economic burden of C. difficile infection and uses the representative national data which is primarily from the database of the Korean Health Insurance Review and Assessme nt Service, for 2008-2011. The annual economic cost was measured using a prevalence approach, which sums the costs incurred to treat C. difficile infection. C. difficile infection prevalence was estimated to have increased from1.43 per 100,000 in 2008 to 5.06 per 100,000 in 2011. Moreover, mortality increased from 69 cases in 2008 to 172 in 2011. The economic cost increased concurrently, from $2.4 million in 2008 to $7.6 million, $10.5 million, and $15.8 million in 2009, 2010, and 2011, respectively. The increasing economic burden of C. difficile infection over the course of the study period emphasizes the need for intervention to minimize the burden of a preventable illness like C. difficile infection.
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