Comparison of sequential and 7-, 10-, 14-d triple therapy for Helicobacter pylori infection
DC Field | Value | Language |
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dc.contributor.author | Choi, Hyuk Soon | - |
dc.contributor.author | Chun, Hoon Jai | - |
dc.contributor.author | Park, Sang Hoon | - |
dc.contributor.author | Keum, Bora | - |
dc.contributor.author | Seo, Yeon Seok | - |
dc.contributor.author | Kim, Yong Sik | - |
dc.contributor.author | Jeen, Yoon-Tae | - |
dc.contributor.author | Um, Soon Ho | - |
dc.contributor.author | Lee, Hong Sik | - |
dc.contributor.author | Kim, Chang Duck | - |
dc.contributor.author | Ryu, Ho Sang | - |
dc.date.accessioned | 2021-12-31T14:40:38Z | - |
dc.date.available | 2021-12-31T14:40:38Z | - |
dc.date.created | 2021-08-30 | - |
dc.date.issued | 2012-05-21 | - |
dc.identifier.issn | 1007-9327 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/133853 | - |
dc.description.abstract | AIM: To compare the effectiveness of sequential therapy for Helicobacter pylori (H. pylori) infection with that of triple therapy of varying durations. METHODS: The 460 patients enrolled in this study had H. pylori-associated gastritis or a gastric or duodenal ulcer. After screening, H. pylori-infected patients were randomly assigned to receive either conventional triple therapy for 7, 10 or 14 d, or a new 10-d sequential therapy. Each of the 4 treatment groups included 115 patients. The outcomes of eradication therapy were assessed 4 wk after treatment by the urea breath test and histology. RESULTS: The overall eradication rate was 81.0%, and eradication rates were 75.7% for 7-d conventional triple therapy, 81.9% for 10-d conventional triple therapy, 84.4% for 14-d conventional triple therapy, and 82.0% for 10-d sequential therapy. Neither intention-to-treat analysis nor per protocol analysis showed significant differences in eradication rates using sequential therapy or the standard triple therapy (P = 0.416 and P = 0.405, respectively). CONCLUSION: There are no significant differences between 10-d sequential eradication therapy for H. pylori and any duration of standard triple treatment in Korean patients. (c) 2012 Baishideng. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | BAISHIDENG PUBLISHING GROUP INC | - |
dc.subject | PROTON-PUMP INHIBITOR | - |
dc.subject | CLARITHROMYCIN-RESISTANT GENOTYPES | - |
dc.subject | RANDOMIZED CLINICAL-TRIAL | - |
dc.subject | ANTIBIOTIC-RESISTANCE | - |
dc.subject | ERADICATION RATE | - |
dc.subject | UNITED-STATES | - |
dc.subject | METAANALYSIS | - |
dc.subject | KOREA | - |
dc.subject | VS. | - |
dc.subject | CHILDREN | - |
dc.title | Comparison of sequential and 7-, 10-, 14-d triple therapy for Helicobacter pylori infection | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Hyuk Soon | - |
dc.contributor.affiliatedAuthor | Chun, Hoon Jai | - |
dc.contributor.affiliatedAuthor | Park, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Keum, Bora | - |
dc.contributor.affiliatedAuthor | Seo, Yeon Seok | - |
dc.contributor.affiliatedAuthor | Kim, Yong Sik | - |
dc.contributor.affiliatedAuthor | Jeen, Yoon-Tae | - |
dc.contributor.affiliatedAuthor | Um, Soon Ho | - |
dc.contributor.affiliatedAuthor | Lee, Hong Sik | - |
dc.contributor.affiliatedAuthor | Kim, Chang Duck | - |
dc.identifier.doi | 10.3748/wjg.v18.i19.2377 | - |
dc.identifier.scopusid | 2-s2.0-84861731083 | - |
dc.identifier.wosid | 000304385300010 | - |
dc.identifier.bibliographicCitation | WORLD JOURNAL OF GASTROENTEROLOGY, v.18, no.19, pp.2377 - 2382 | - |
dc.relation.isPartOf | WORLD JOURNAL OF GASTROENTEROLOGY | - |
dc.citation.title | WORLD JOURNAL OF GASTROENTEROLOGY | - |
dc.citation.volume | 18 | - |
dc.citation.number | 19 | - |
dc.citation.startPage | 2377 | - |
dc.citation.endPage | 2382 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.subject.keywordPlus | PROTON-PUMP INHIBITOR | - |
dc.subject.keywordPlus | CLARITHROMYCIN-RESISTANT GENOTYPES | - |
dc.subject.keywordPlus | RANDOMIZED CLINICAL-TRIAL | - |
dc.subject.keywordPlus | ANTIBIOTIC-RESISTANCE | - |
dc.subject.keywordPlus | ERADICATION RATE | - |
dc.subject.keywordPlus | UNITED-STATES | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | KOREA | - |
dc.subject.keywordPlus | VS. | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordAuthor | Helicobacter pylori | - |
dc.subject.keywordAuthor | Sequential therapy | - |
dc.subject.keywordAuthor | Triple therapy | - |
dc.subject.keywordAuthor | Gastric ulcer | - |
dc.subject.keywordAuthor | Duodenal ulcer | - |
dc.subject.keywordAuthor | Gastritis | - |
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