Isolation of a Klebsiella pneumoniae Isolate of Sequence Type 258 Producing KPC-2 Carbapenemase in Korea
- Authors
- Roh, Kyoung Ho; Lee, Chang Kyu; Sohn, Jang Wook; Song, Wonkeun; Yong, Dongeun; Lee, Kyungwon
- Issue Date
- 10월-2011
- Publisher
- KOREAN SOC LABORATORY MEDICINE
- Keywords
- KPC-2; Klebsiella pneumoniae; ST258
- Citation
- KOREAN JOURNAL OF LABORATORY MEDICINE, v.31, no.4, pp.298 - 301
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- KOREAN JOURNAL OF LABORATORY MEDICINE
- Volume
- 31
- Number
- 4
- Start Page
- 298
- End Page
- 301
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/134211
- DOI
- 10.3343/kjlm.2011.31.4.298
- ISSN
- 1598-6535
- Abstract
- Carbapenem-resistant Klebsiella pneumoniae isolates producing K. pneumoniae carbapenemases (KPC) were first reported in the USA in 2001, and since then, this infection has been reported in Europe, Israel, South America, and China. In Korea, the first KPC-2-producing K. pneumoniae sequence type (ST) 11 strain was detected in 2010. We report the case of a patient with a urinary tract infection caused by KPC-2-producing K. pneumoniae. This is the second report of a KPC-2-producing K. pneumoniae infection in Korea, but the multilocus sequence type was ST258. The KPC-2-producing isolate was resistant to all tested beta-lactams (including imipenem and meropenem), amikacin, tobramycin, ciprofloxacin, levofloxacin, and trimethoprim-sulfamethoxazole, but was susceptible to gentamicin, colistin, polymyxin B, and tigecycline. The KPC-2-producing isolate was negative to phenotypic extended-spectrum beta-lactamase (ESBL) and AmpC detection tests and positive to modified Hodge test and carbapenemase inhibition test with aminophenylboronic acid.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
- Graduate School > Department of Biomedical Sciences > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.