Transesophageal Echocardiography in Ischemic Stroke With Atrial Fibrillation
DC Field | Value | Language |
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dc.contributor.author | Tanaka, Kanta | - |
dc.contributor.author | Koga, Masatoshi | - |
dc.contributor.author | Lee, Keon-Joo | - |
dc.contributor.author | Kim, Beom Joon | - |
dc.contributor.author | Mizoguchi, Tadataka | - |
dc.contributor.author | Park, Eun Lyeong | - |
dc.contributor.author | Lee, Juneyoung | - |
dc.contributor.author | Yoshimura, Sohei | - |
dc.contributor.author | Cha, Jae-Kwan | - |
dc.contributor.author | Lee, Byung-Chul | - |
dc.contributor.author | Koge, Junpei | - |
dc.contributor.author | Bae, Hee-Joon | - |
dc.contributor.author | Toyoda, Kazunori | - |
dc.date.accessioned | 2022-02-14T07:40:49Z | - |
dc.date.available | 2022-02-14T07:40:49Z | - |
dc.date.created | 2022-01-19 | - |
dc.date.issued | 2021-11-16 | - |
dc.identifier.issn | 2047-9980 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/135717 | - |
dc.description.abstract | BACKGROUND: To clarify differences in clinical significance of intracardiac thrombi in nonvalvular atrial fibrillation-associated stroke as identified by transesophageal echocardiography (TEE) and transthoracic echocardiography (TTE). METHODS AND RESULTS: Using patient data on nonvalvular atrial fibrillation-associated ischemic stroke between 2011 and 2014 from 15 South Korean stroke centers (n=4841) and 18 Japanese centers (n=1192), implementation rates of TEE/TTE, and detection rates of intracardiac thrombi at each center were correlated. The primary outcome was recurrent ischemic stroke at 1 year after the onset. A total of 5648 patients (median age, 75 years; 2650 women) were analyzed. Intracardiac thrombi were detected in 75 patients (1.3%) overall. Thrombi were detected in 7.8% of patients with TEE (either TEE alone or TEE+TTE: n=679) and in 0.6% of those with TTE alone (n=3572). Thrombus detection rates varied between 0% and 14.3% among centers. As TEE implementation rates at each center increased from 0% to 56.7%, thrombus detection rates increased linearly (detection rate [%]=0.11xTEE rate [%]+1.09 [linear regression], P<0.01). TTE implementation rates (32.3%-100%) were not associated with thrombus detection rates (P=0.53). Intracardiac thrombi were associated with risk of recurrent ischemic stroke overall (adjusted hazard ratio [aHR] 2.35, 95% CI, 1.07-5.16). Thrombus-associated ischemic stroke risk was high in patients with TEE (aHR, 3.13; 95% CI, 1.17-8.35), but not in those with TTE alone (aHR, 0.89; 95% CI, 0.12-6.51). CONCLUSIONS: Our data suggest clinical relevance of TEE for accurate detection and risk stratification of intracardiac thrombi in nonvalvular atrial fibrillation-associated stroke. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.subject | APPENDAGE OCCLUSION | - |
dc.subject | RISK-FACTORS | - |
dc.subject | THROMBUS | - |
dc.subject | THROMBOEMBOLISM | - |
dc.subject | ASSOCIATION | - |
dc.subject | SCALE | - |
dc.title | Transesophageal Echocardiography in Ischemic Stroke With Atrial Fibrillation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Juneyoung | - |
dc.identifier.doi | 10.1161/JAHA.121.022242 | - |
dc.identifier.scopusid | 2-s2.0-85120776633 | - |
dc.identifier.wosid | 000718875100001 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE AMERICAN HEART ASSOCIATION, v.10, no.22 | - |
dc.relation.isPartOf | JOURNAL OF THE AMERICAN HEART ASSOCIATION | - |
dc.citation.title | JOURNAL OF THE AMERICAN HEART ASSOCIATION | - |
dc.citation.volume | 10 | - |
dc.citation.number | 22 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | APPENDAGE OCCLUSION | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | SCALE | - |
dc.subject.keywordPlus | THROMBOEMBOLISM | - |
dc.subject.keywordPlus | THROMBUS | - |
dc.subject.keywordAuthor | atrial fibrillation | - |
dc.subject.keywordAuthor | echocardiography | - |
dc.subject.keywordAuthor | stroke | - |
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